8 documents found, page 1 of 1
Special Report: The Biology of Inequalities in Health: The Lifepath Consortium
Vineis, P; Avendano-Pabon, M; Barros, H; Bartley, M; Carmeli, C; Carra, L; Chadeau-Hyam, M; Costa, G; Delpierre, C; D'Errico, A; Fraga, S; Giles, GFunded by the European Commission Horizon 2020 programme, the Lifepath research consortium aimed to investigate the effects of socioeconomic inequalities on the biology of healthy aging. The main research questions included the impact of inequalities on health, the role of behavioral and other risk factors, the underlying biological mechanisms, the efficacy of selected policies, and the general implications of ...
Patterning of educational attainment across inflammatory markers: Findings from...
Maurel, M; Castagné, R; Berger, E; Bochud, M; Chadeau-Hyam, M; Fraga, S; Gandini, M; Hutri-Kähönen, N; Jalkanen, S; Kivimäki, M; Marmot, M; McCrory, CBackground. Evidence suggests that the inflammatory reaction, an adaptive response triggered by a variety of harmful stimuli and conditions involved in the risk and development of many chronic diseases, is a potential pathway through which the socioeconomic environment is biologically embedded. Difficulty in interpreting the role of the inflammatory system in the embodiment dynamic arises because of heterogenei...
The contribution of sleep to social inequalities in cardiovascular disorders: a...
Petrovic, D; Haba-Rubio, J; de Mestral, Vargas, C; Kelly-Irving, M; Vineis, P; Kivimäki, M; Nyberg, S; Gandini, M; Bochud, M; Vollenweider, PAims: Sleep disturbances exhibit a strong social patterning, and inadequate sleep has been associated with adverse health outcomes, including cardiovascular disorders (CVD). However, the contribution of sleep to socioeconomic inequalities in CVD is unclear. This study pools data from eight European cohorts to investigate the role of sleep duration in the association between life-course socioeconomic status (SES...
Neighbourhood socioeconomic deprivation and allostatic load: a multi-cohort study
Ribeiro, AI; Fraga, S; Kelly-Irving, M; Delpierre, C; Stringhini, S; Kivimaki, M; Joost, S; Guessous, I; Gandini, M; Vineis, P; Barros, HLiving in deprived neighbourhoods may have biological consequences, but few studies have assessed this empirically. We examined the association between neighbourhood deprivation and allostatic load, a biological marker of wear and tear, taking into account individual’s socioeconomic position. We analysed data from three cohort studies (CoLaus-Switzerland; EPIPorto-Portugal; Whitehall II-UK) comprising 16,364 pa...
Allostatic load and subsequent all-cause mortality: which biological markers dr...
Castagné, R; Garès, V; Karimi, M; Chadeau-Hyam, M; Vineis, P; Delpierre, C; Kelly-Irving, MThe concept of allostatic load (AL) refers to the idea of a global physiological 'wear and tear' resulting from the adaptation to the environment through the stress response systems over the life span. The link between socioeconomic position (SEP) and mortality has now been established, and there is evidence that AL may capture the link between SEP and mortality. In order to quantitatively assess the role of AL...
Socioeconomic status, non-communicable disease risk factors, and walking speed ...
Stringhini, S; Carmeli, C; Jokela, M; Avendaño, M; McCrory, C; d'Errico, A; Bochud, M; Barros, H; Costa, G; Chadeau-Hyam, M; Delpierre, C; Gandini, MObjective To assess the association of low socioeconomic status and risk factors for non-communicable diseases (diabetes, high alcohol intake, high blood pressure, obesity, physical inactivity, smoking) with loss of physical functioning at older ages. Design Multi-cohort population based study. Setting 37 cohort studies from 24 countries in Europe, the United States, Latin America, Africa, and Asia, 1990-2017 P...
Socioeconomic status and the 25 × 25 risk factors as determinants of premature ...
Stringhini, S; Carmeli, C; Jokela, M; Avendaño, M; Muennig, P; Guida, F; Ricceri, F; d'Errico, A; Barros, H; Bochud, M; Chadeau-Hyam, MBackground: In 2011, WHO member states signed up to the 25 × 25 initiative, a plan to cut mortality due to non-communicable diseases by 25% by 2025. However, socioeconomic factors influencing non-communicable diseases have not been included in the plan. In this study, we aimed to compare the contribution of socioeconomic status to mortality and years-of-life-lost with that of the 25 × 25 conventional risk facto...
Development of a cross-cultural deprivation index in five European countries
Guillaumel, E; Pornet, C; Dejardin, O; Launay, L; Lillini, R; Vercelli, M; Marí-Dell'Olmo, M; Fontelo, AF; Borrell, C; Ribeiro, AI; Pina, MF; Mayer, ABACKGROUND:Despite a concerted policy effort in Europe, social inequalities in health are a persistent problem. Developing a standardised measure of socioeconomic level across Europe will improve the understanding of the underlying mechanisms and causes of inequalities. This will facilitate developing, implementing and assessing new and more effective policies, and will improve the comparability and reproducibi...