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Developmental motor problems and health-related quality of life in 5-year-old c...

Aubert, AM; Costa, R; Johnson, S; Ådén, U; Pierrat, V; Cuttini, M; Männamaa, M; Sarrechia, I; Lebeer, J; Van Heijst, AF; Maier, RF; Sentenac, M

Aim To measure the association between cerebral palsy (CP) and non-CP-related movement difficulties and health-related quality of life (HRQoL) among 5-year-old children born extremely preterm (<28 weeks gestational age). Method We included 5-year-old children from a multi-country, population-based cohort of children born extremely preterm in 2011 to 2012 in 11 European countries (n = 1021). Children without CP ...


Health-related quality of life of children born very preterm: a multinational E...

Kim, SW; Andronis, L; Seppänen, AV; Aubert, AM; Barros, H; Draper, ES; Sentenac, M; Zeitlin, J; Petrou, S; SHIPS Research Group

Purpose This study aims to (1) describe the health-related quality of life (HRQoL) outcomes experienced by children born very preterm (28–31 weeks’ gestation) and extremely preterm (< 28 weeks’ gestation) at five years of age and (2) explore the mediation effects of bronchopulmonary dysplasia (BPD) and severe non-respiratory neonatal morbidity on those outcomes. Methods This investigation was based on data for ...


Maternal education and cognitive development in 15 European very-preterm birth ...

Sentenac, M; Benhammou, V; Aden, U; Ancel, PY; Bakker, LA; Bakoy, H; Barros, H; Baumann, N; Bilsteen, JF; Boerch, K; Croci, I; Cuttini, M; Draper, E

Background Studies are sparse and inconclusive about the association between maternal education and cognitive development among children born very preterm (VPT). Although this association is well established in the general population, questions remain about its magnitude among children born VPT whose risks of medical and developmental complications are high. We investigated the association of maternal education...


Maternal education and language development at 2 years corrected age in childre...

Sentenac, M; Johnson, S; Charkaluk, ML; Sëppanen, AV; Aden, U; Cuttini, M; Maier, R; Mannamaa, M; Zeitlin, J; EPICE group

Background Socioeconomic factors influence language development in the general population, but the association remains poorly documented in children born very preterm (VPT). We assessed the impact of maternal education on language development in children born VPT and effect modification by perinatal risk. Methods Data were from the Effective Perinatal Intensive Care in Europe (EPICE) population-based cohort of ...


Priorities for collaborative research using very preterm birth cohorts

Zeitlin, J; Sentenac, M; Morgan, AS; Ancel, PY; Barros, H; Cuttini, M; Draper, E; Johnson, S; Lebeer, J; Maier, RF; Norman, M; Varendi, H

Objectives To develop research priorities on the consequences of very preterm (VPT) birth for the RECAP Preterm platform which brings together data from 23 European VPT birth cohorts. Design and setting This study used a two-round modified Delphi consensus process. Round 1 was based on 28 research themes related to childhood outcomes (<12 years) derived from consultations with cohort researchers. An external pa...


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