16 documents found, page 1 of 2
miRNAs in Heart Development and Disease
Lozano-Velasco, Estefania; Inácio, José Manuel; Sousa, Inês; Guimarães, Ana Rita; Franco, Diego; Moura, Gabriela; A. Belo, JoséFunding Information: This work was supported by funds from the Fundação para a Ciência e a Tecnologia (NETDIAMOND-SAICTPAC/0047/2015), iNOVA4Health-UID/Multi/04462/2020, and LS4FUTURE Associated Laboratory (LA/P/0087/2020) to J.A.B. and funds from the Scientific Employment Stimulus to J.M.I. (Norma Transitória 8189/2018). This work was also support by grants from the Ministry of Education and Science of the Spa...
Gene-Edited Human-Induced Pluripotent Stem Cell Lines to Elucidate DAND5 Functi...
Inácio, José M; Nunes, Mafalda M; Almeida, Micael; Cristo, Fernando; Anjos, Rui; A. Belo, JoséFunding: This work was supported by Fundação para a Ciência e a Tecnologia (PTDC/ BIMMED/3363/2014) and Scientific Employment Stimulus to J.M.I. (Norma Transitória 8189/2018), predoctoral fellowship to M.A. (FCT; 06890/2021/BD), post-doctoral fellowship to F.C. (DAI 2019/08/ SAICTPAC/0047/2015) and iNOVA4Health – UIDB/04462/2020 and UIDP/04462/2020, two programs financially supported by Fundação para a Ciência ...
CCBE1 in Cardiac Development and Disease
Bonet, Fernando; Inácio, José M.; Bover, Oriol; Añez, Sabrina B.; A. Belo, JoséFunding Information: Funding: OB was a pre-doctoral fellow of Fundação para a Ciência e Tecnologia (PD/BD/105891/2015). This work was supported by Fundação para a Ciência e a Tecnologia (FCT) grants (PTDC/SAU-ENB/121095/2010, HMSP-ICT/0039/2013 and 02/SAICT/2017/029590) to JA Belo and by the Scientific Employment Stimulus to JMI (Norma Transitória 8189/2018, FCT), and iNOVA4Health – UIDB/Multi/04462/2020 and UI...
DAND5 Inactivation Enhances Cardiac Differentiation in Mouse Embryonic Stem Cells
Inácio, José Manuel; von Gilsa Lopes, João; Silva, Ana Mafalda; Cristo, Fernando; Marques, Sara; Futschik, Matthias E.; A. Belo, JoséFunding: This work was supported by the Fundação para a Ciência e a Tecnologia (PTDC/BIM-MED/3363/2014) and Scientific Employment Stimulus to JI (Norma Transitória 8189/2018), predoctoral fellowship to JG (FCT; PD/BD/136919/2018) and postdoctoral fellowship to FC (DAI/ 2019/08/SAICTPAC/0047/2015), and iNOVA4Health-UID/Multi/04462/2013, a program financially supported by Fundação para a Ciência e a Tecnologia/Mi...
Generation of a gene-corrected human induced pluripotent stem cell line derived...
Inácio, José M.; Almeida, Micael; Cristo, Fernando; A. Belo, JoséThis work was supported by Fundação para a Ciência e a Tecnologia (PTDC/ BIM-MED/3363/2014) and iNOVA4Health -UID/Multi/04462/ 2013, a program financially supported by Fundação para a Ciência e Tecnologia/ Ministério da Educação e Ciência, through national funds and co-funded by FEDER under the PT2020 Partnership Agreement.; Human induced pluripotent stem cells (hiPSCs) from individual patient basis are conside...
Loss of Ccbe1 affects cardiac-specification and cardiomyocyte differentiation i...
Bover, Oriol; Justo, Tiago; Pereira, Paulo N G; Facucho-Oliveira, João; Inácio, José M; Ramalho, José S; Domian, Ibrahim J; A. Belo, JoséTJ was a pre-doctoral fellow of Fundacao para a Ciencia e Tecnologia (FCT; SFRH/BD/82280/2011), JFO (SFRH/BPD/46506/2008), JI (CEDOC/2015/36/iNOVA4Health/Multi/04462) and PNGP (SFRH/BPD/87114/2012) are FCT post-doctoral fellows. This work was supported by FCT grants (PTDC/SAU-ENB/121095/2010 and HMSP-ICT/0039/2013) to JA Belo. iNOVA4Health - UID/Multi/04462/2013, a program financially supported by Fundacao para...
Generation and characterization of a human iPS cell line from a patient-related...
Pars, Selin; Cristo, Fernando; Inácio, José M; Rosas, Graça; Carreira, Isabel Marques; Melo, Joana Barbosa; Mendes, Patrícia; Martins, Duarte SaraivaWe would like to thank the patient and their guardians for their generous donation of the urine sample used in this study. We also would like to thank Ana Jardim for technical support in karyotype analysis. This work was supported by Fundacao para a Ciencia e a Tecnologia (PTDC/BIM-MED/3363/2014). iNOVA4Health - UID/Multi/04462/2013, a program financially supported by Fundacao para a Ciencia e Tecnologia/Minist...
The Role of Cerl2 in the Establishment of Left-Right Asymmetries during Axis Fo...
A. Belo, José; Marques, Sara; Inácio, José MThis work was supported by Fundação para a Ciência e a Tecnologia (PTDC/BIM-MED/3363/2014). iNOVA4Health—UID/Multi/04462/2013, a program financially supported by Fundação para a Ciência e Tecnologia/Ministério da Educação e Ciência, through national funds and co-funded by FEDER under the PT2020 Partnership Agreement is acknowledged.; The formation of the asymmetric left-right (LR) body axis is one of the fundam...
Functional study of DAND5 variant in patients with Congenital Heart Disease and...
Cristo, F.; Inácio, J.M.; de Almeida, S.; Mendes, P.; Martins, D.S.; Maio, J.; Anjos, R.; A. Belo, JoséBackground: Perturbations on the Left-Right axis establishment lead to laterality defects, with frequently associated Congenital Heart Diseases (CHDs). Indeed, in the last decade, it has been reported that the etiology of isolated cases of CHDs or cases of laterality defects with associated CHDs is linked with variants of genes involved in the Nodal signaling pathway. Methods: With this in mind, we analyzed a c...
Generation of human iPSC line from a patient with laterality defects and associ...
Cristo, Fernando; Inácio, José M.; Rosas, Graça; Carreira, Isabel Marques; Melo, Joana Barbosa; de Almeida, Luís Pereira; Mendes, PatríciaWe would like to thank the patient and their guardians for their generous donation of the urine sample used in this study. We also would like to thank Ana Jardimfor technical support in karyotype analysis. This work was supported by Fundacao para a Ciencia e a Tecnologia (PTDC/BIM-MED/3363/2014). iNOVA4Health - UID/Multi/04462/2013, a program financially supported by Fundacao para a Ciencia e Tecnologia/Ministe...