4 documents found, page 1 of 1
Inflammatory patterns in fixed airflow obstruction are dependent on the presenc...
Mogensen, I; Jacinto, T; Alving, K; Fonseca, JA; Janson, C; Malinovschi, ARationale: Fixed airflow obstruction (FAO) can complicate asthma. Inflammation is a proposed underlying mechanism. Objective: Our aim in this cross-sectional investigation was to evaluate the blood leucocyte pattern and level of exhaled nitric oxide in asthmatics and non-asthmatics with or without FAO. Methods: A total of 11,579 individuals aged ≥20 years from the US National Health and Nutrition Examination Su...
Identification of asthma phenotypes in the US general population: A latent clas...
Amaral, Rita; Pereira, Ana M; Jacinto, Tiago; Malinovsch, A; Janson, C; Alving, K; Fonseca, J. A.Combining clinical and physiological data from adults with asthma by means of unsupervised classification methods could provide a better taxonomy among the general asthma population. Therefore, we aimed to identify distinct phenotypes using latent class analysis (LCA), in adults with current asthma from the general population.
Setting reference values for exhaled nitric oxide: a systematic review
Jacinto, T; Alving, K; Correia, R; Costa-Pereira, A; Fonseca, JABACKGROUND: The values obtained when the fraction of exhaled nitric oxide (FeNO) is measured are affected by several factors that are specific to the individual patient, making interpretation difficult, especially in the initial assessment of patients with respiratory symptoms. METHODS: Systematic review of studies on FeNO reference values and individual-specific factors that influence them. RESULTS: From 3739 ...
Exhaled nitric oxide levels and blood eosinophil counts independently associate...
Malinovschi, A; Fonseca, JA; Jacinto, T; Alving, K; Janson, CBACKGROUND: Fraction of exhaled nitric oxide (Feno) and blood eosinophil count (B-Eos) values, markers of local and systemic eosinophilic inflammation, respectively, are increased in asthmatic patients. Little is known about the relation of these markers to reported wheeze and asthma events in a random population sample. OBJECTIVES: We sought to determine the individual and independent values of B-Eos and Feno ...