5 documents found, page 1 of 1
Avaliação das alterações hipocampais em camundongos c57bl/6j desafiados pela Hi...
Alves, Ana Carolina Benicio; Frota, Priscila Briseno; Campelo, Marcio Wilker Soares; Alves, Luis Antonio de Oliveira; Pinto, Daniel VieiraALVES, Ana Carolina Benicio et al. Avaliação das alterações hipocampais em camundongos c57bl/6j desafiados pela Hiperlipidemia e dieta regional básica. Revista Encontros Universitários da UFC, Fortaleza, v. 1, n. 1, 2016. (Encontro de Iniciação Científica, 35); A obesidade é cada vez mais frequente em crianças expostas à uma dieta rica em lipídios no semiárido brasileiro, podendo causar déficits cognitivos. Com...
Pré-condicionamento com nitrosil rutênio promove neuroproteção cerebral envolve...
Campelo, Marcio Wilker SoaresBackground and purpose - The NO donors can decrease neuronal injury during cerebral ischemia and reperfusion (I/R) by increasing the blood flow to the brain. The objective of this study is to study whether a new nitrosyl ruthenium complex makes some effect during I/R and if involves protein kinases. Methods - Used 180 male rats, Wistar rats, with an average weight of 290.27 g, distributed 6 groups: Sham 1h, sal...
Preconditioning with L-alanyl-glutamine upon cerebral edema and hypocampus red ...
Vasconcelos, Paulo Roberto Cavalcante de; Guimarães, André Brito Bastos; Campelo, Marcio Wilker Soares; Vasconcelos, Paulo Roberto Leitão dePURPOSE: To evaluate the effects of the dipeptide L-alanyl-glutamine (L-Ala-Gln) as a preconditioning agent to potentially promote reduction in the intensity of lesion or induction of resilience in rats subjected to global cerebral ischemia/reperfusion (I/R) injury. METHODS: Thirty-six male Wistar rats weighing 280-300g were randomly assigned to six groups (n=6). Groups Sham 1h and 24h were treated with saline ...
Efeitos do nitrosil rutênio na lesão cerebral induzida por isquemia e reperfusã...
Campelo, Marcio Wilker SoaresBackground and purpose - Nitric oxide (NO) donors are known to reduce neuronal damage during brain ischemia and reperfusion by increasing the blood flow. Rut-bpy is a novel nitrosyl-ruthenium complex releasing NO directly into the vascular smooth musculature. The objective of the study was to evaluate the effect of Rut-bpy on a rat model of brain ischemia and reperfusion. Methods - Ninety-six male Wistar rats w...
Preconditioning with a novel metallopharmaceutical NO donor in anesthetized rat...
Oriá, Reinaldo Barreto; Lopes, Luiz Gonzaga de França; Brito, Gerly Anne de Castro; Santos, Armenio Aguiar dos; Vasconcelos, Raquel Cavalcante deRut-bpy is a novel nitrosyl–ruthenium complex releasing NO into the vascular system. We evaluated the effect of Rut-bpy (100 mg/kg) on a rat model of brain stroke. Forty rats were assigned to four groups (Saline solution [SS], Rut-bpy, SS?ischemia–reperfusion [SS?I/ R] and Rut-bpy?ischemia–reperfusion [Rut-bpy?I/R]) with their mean arterial pressure (MAP) continuously monitored. The groups were submitted (SS?I/...