6 documents found, page 1 of 1
Doença de Hirayama: Relato de um Caso Clínico de Sucesso
David Moura; Rafael Martins; Diana Oliveira; Ana Romeiro; Sofia Azevedo; Joana Ramalho; Sara Ribeiro Silva; Pedro Cubelo Pereira; Branco C
Components of essential oils - A promise land to combat methicillin-resistant S...
Anabela Borges; Luís Costa; Diana Oliveira; Simões M
2-(2-Methyl-2-nitrovinyl)furan but Not Furvina Interfere with Staphylococcus au...
Diana Oliveira; Anabela Borges; Reinaldo Molina Ruiz; Zenaida Rodríguez Negrín; Simona Distinto; Fernanda Borges; Manuel SimõesQuorum sensing (QS) plays an essential role in the production of virulence factors, in biofilm formation and antimicrobial resistance. Consequently, inhibiting QS is being considered a promising target for antipathogenic/anti-virulence therapies. This study aims to screen 2-nitrovinylfuran derivatives structurally related to Furvina (a broad-spectrum antibiotic already used for therapeutic purposes) for their e...
Biofilms in Diabetic Foot Ulcers: Impact, Risk Factors and Control Strategies
Ana Afonso; Diana Oliveira; Maria José Saavedra; Anabela Borges; Manuel SimõesDiabetic foot ulcers (DFUs) are a serious complication from diabetes mellitus, with a huge economic, social and psychological impact on the patients' life. One of the main reasons why DFUs are so difficult to heal is related to the presence of biofilms. Biofilms promote wound inflammation and a remarkable lack of response to host defences/treatment options, which can lead to disease progression and chronicity. ...
Staphylococcus aureus Toxins and Their Molecular Activity in Infectious Diseases
Diana Oliveira; Anabela Borges; Manuel SimõesStaphylococcus aureus is a microorganism resident in the skin and nasal membranes with a dreadful pathogenic potential to cause a variety of community and hospital-acquired infections. The frequency of these infections is increasing and their treatment is becoming more difficult. The ability of S. aureus to form biofilms and the emergence of multidrug-resistant strains are the main reasons determining the chall...
Biofilms and antibiotic susceptibility of multidrug-resistant bacteria from wil...
Carla Dias; Anabela Borges; Diana Oliveira; Antonio Martinez-Murcia; Maria José Saavedra; Manuel SimõesBackground. The "One Health" concept recognizes that human health and animal health are interdependent and bound to the health of the ecosystem in which they (co)exist. This interconnection favors the transmission of bacteria and other infectious agents as well as the flow of genetic elements containing antibiotic resistance genes. This problem is worsened when pathogenic bacteria have the ability to establish ...