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O processo de vinculação do pai com o recém-nascido: uma revisão narrativa

Poeiras, A; Dias, A; Condinho, L; Cerdeira, R; Frias, A

Enquadramento: No processo de vinculação são várias as dimensões que interferem com o mesmo, sendo relevante que logo após o nascimento se estabeleça o mais precoce possível a vinculação pai-Recém-Nascido (RN). Objetivo: Sistematizar a evidência sobre o processo de vinculação do pai com o RN. Método: Revisão integrativa da literatura, através das bases de dados, via EBSCO, CINAHL Plus with full texto, Cochrane ...



Evaluation of urinary cysteinyl leukotrienes as biomarkers of severity and puta...

Reina-Couto, M; Roboredo-Madeira, M; Pereira-Terra, P; Silva-Pereira, C; Martins, S; Teixeira-Santos, L; Pinho, D; Dias, A; Cordeiro, G; Dias, CC

Background Cysteinyl leukotrienes (CysLT) are potent inflammation-promoting mediators, but remain scarcely explored in COVID-19. We evaluated urinary CysLT (U-CysLT) relationship with disease severity and their usefulness for prognostication in hospitalized COVID-19 patients. The impact on U-CysLT of veno-venous extracorporeal membrane oxygenation (VV-ECMO) and of comorbidities such as hypertension and obesity ...


Non-Vitamin K Oral Anticoagulants Assessment in High Risk of Bleeding Patients ...

Silva Cunha, P; Viveiros Monteiro, A; Coutinho Cruz, M; Malveiro, P; Reis, JP; Portugal, G; Dias, A; Cruz Ferreira, R; Oliveira, MM

Atrial fibrillation (AF) is commonly associated with advanced age and the presence of multiple, concomitant acute and chronic health conditions, placing this population at high risk for serious therapeutic side effects. Nonvitamin K antagonist oral anticoagulants (NOACs) are increasingly used for stroke prevention in patients with atrial fibrillation. The purpose of this study was to investigate the effectivene...


A Case of Central Nervous System Infection by Candida Famata in an Immunosuppre...

Caria, J; Leal, E; Dias, A; Pinheiro, H; Póvoas, D; Maltez, F

Invasive fungal infections caused by Candida species are increasingly observed in immunosuppressed patients. Candida albicans is the more often identified species and neurocandidiasis is associated with high mortality rates. Diagnosis and treatment of these infections are frequently challenging. We report a case of central nervous system infection caused by Candida famata in an HIV-1 infected patient. To our be...


Sequelas da COVID-19 Evidência Atual

Moura, DL; Dias, A; Farinha, PM; Farinha, JM; Robalo-Cordeiro, C

A epidemia de Coronavirus Disease 2019 disseminou-se pelo mundo em poucos meses, levando à sua designação de pandemia. Múltiplas medidas de saúde pública foram implementadas nos países afetados para conter e mitigar a disseminação da doença. A necessidade de distanciamento físico leva a que esta pandemia tenha um impacto importante na sociedade e particularmente no desporto, provocando cancelamento e adiamento ...


Seroprevalence of SARS-CoV-2 Infection in Portugal in May-July 2020: Results of...

Kislaya, I; Gonçalves, P; Barreto, M; Sousa, R; Garcia, AC; Matos, R; Guiomar, R; Rodrigues, AP; Dias, A

Introduction: The aim of this study was to estimate and describe the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) specific antibodies (immunoglobulin M and/or immunoglobulin G) in Portugal in May-July 2020. Material and methods: A cross-sectional seroepidemiological survey was developed after the peak of the first epidemic wave on a sample of 2301 Portuguese residents, aged 1 year ...


Thromboembolic Risk in COVID-19 Patients: Is There a Hidden Link?

Cidade, J; Pinheiro, H; Dias, A; Santos, M; Nascimento, B; Figueiredo, C; Pinto, R; Pereira, L; Rodrigues, C; Maltez, F

Background Although evidence has emerged indicating that patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia present a high risk of venous thromboembolism (VTE), its real incidence and best diagnosis course remain unclear. In this study, we aimed to determine the incidence of pulmonary embolism in these patients and the role of D-dimer serum level as a predictive factor of a new...


Biomarkers and Genetic Modulators of Cerebral Vasculopathy in Sub-Saharan Ances...

Silva, M; Vargas, S; Coelho, A; Ferreira, E; Mendonça, J; Vieira, L; Maia, R; Dias, A; Ferreira, T; Morais, A; Soares, IM; Lavinha, J; Silva, R

We investigated biomarkers and genetic modulators of the cerebral vasculopathy (CV) subphenotype in pediatric sickle cell anemia (SCA) patients of sub-Saharan African ancestry. We found that one VCAM1 promoter haplotype (haplotype 7) and VCAM1 single nucleotide variant rs1409419_T were associated with stroke events, stroke risk, as measured by time-averaged mean of maximum velocity in the middle cerebral artery...


Biomarkers and genetic modulators of cerebral vasculopathy in sub-Saharan ances...

Silva, M; Vargas, S; Coelho, A; Ferreira, E; Mendonça, J; Vieira, L; Maia, R; Dias, A; Ferreira, T, et al.

We investigated biomarkers and genetic modulators of the cerebral vasculopathy (CV) subphenotype in pediatric sickle cell anemia (SCA) patients of sub-Saharan African ancestry. We found that one VCAM1 promoter haplotype (haplotype 7) and VCAM1 single nucleotide variant rs1409419_T were associated with stroke events, stroke risk, as measured by time-averaged mean of maximum velocity in the middle cerebral artery...


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