5 documents found, page 1 of 1
Characterization of Haemophilus influenzae non-invasive disease in children, in...
Duarte, Sara; Bajanca Lavado, Maria Paula; Portuguese Group for the Study of Haemophilus influenzae Invasive InfectionBackground: Haemophilus influenzae is a Gram-negative bacterium that colonizes the human upper respiratory tract, where it can remain asymptomatic. It can also progress from colonizer to pathogen and cause acute mucosal infections, such as otitis and conjunctivitis, particularly in children. These infections are frequently associated to NTHi H. influenzae. Empirical treatment with antibiotics is of concern due ...
Characterization of Haemophilus influenzae from healthy children attending day-...
Bajanca Lavado, Maria Paula; Cavaco, Luís Filipe; Fernandes, Mariana; Touret, Tiago; Candeias, CatarinaHaemophilus influenzae colonizes the human upper respiratory tract, where it can remain asymptomatically. It can also progress from colonizer to pathogen and cause mucosal or invasive infections. The aim of this study was to unravel epidemiological aspects of H. influenzae nasopharyngeal colonization in healthy children attending day-care centers in Portugal. Methods Between 2015 and 2019, 1518 nasopharyngeal s...
Haemophilus influenzae Serotype b Vaccines: Public Health Impact in Prevention ...
Bajanca Lavado, Maria PaulaWorldwide vaccination introduction in the National Immunization Programs have contributed to control and prevent a considerable number of diseases. This is one of most relevant Public Health resources in the area of prevention and control of diseases and epidemics. The human-restricted bacterium Haemophilus influenzae is responsible for respiratory infections in both children and adults. While colonization begi...
Haemophilus influenzae serotype b vaccine failure in Portugal: a new threat?
Bajanca Lavado, Maria Paula; Bettencourt, Célia; Cunha, Florbela; Marques, José GonçaloIntroduction and Aims: Invasive disease due to Haemophilus influenzae type-b (Hib) suffered a dramatic reduction in countries that introduced routine immunization of infants with the conjugate vaccine. However, along with the relative increase of H. influenzae non-typeable invasive strains (NTHI), the emergence of non-b serotypes as well as Hib disease due to vaccine failure (VF) have been described.1- 4 The ai...
Haemophilus influenzae invasive disease in Portugal, 2017-2018 - what have been...
Bettencourt, Célia; Bajanca Lavado, Maria Paula; The Portuguese Group for the “Study of Haemophilus influenzae invasive infection”Introduction and Aims: Haemophilus influenzae is a frequent colonizer of the upper airways that can easily spread through respiratory tract leading to invasive infections in both children and adults. H. influenzae serotype b (Hib) has been prevented by vaccination, in Portugal, since 2000, but the emergence of non-typeable isolates (NTHi), as well as non-b serotypes responsible for invasive disease have been do...