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Effect of gamma-radiation on zearalenone—degradation, cytotoxicity and estrogen...

Calado, Thalita; Abrunhosa, Luís; Cabo Verde, Sandra; Alté, Luis; Venâncio, Armando; Fernández-Cruz, María Luisa

Zearalenone (ZEA) is produced in cereals by different species of Fusarium, being a non-steroidal estrogenic mycotoxin. Despite having a low acute toxicity, ZEA strongly interferes with estrogen receptors. Gamma-radiation has been investigated to eliminate mycotoxins from food and feed, showing promising results. The present study aims to investigate the gamma-radiation effect on ZEA at different moisture condit...


Gamma irradiation effects on ochratoxin A: degradation, cytotoxicity and applic...

Calado, Thalita; Fernández-Cruz, María Luisa; Verde, Sandra Cabo; Venâncio, Armando; Abrunhosa, Luís

Ochratoxin A (OTA) is one of the main mycotoxins that can be found in food. The use of gamma radiation is a technique for preserving food that may exert some effects on mycotoxins. OTA was irradiated in its dry form, in aqueous and in methanolic solutions, and in wheat flour, grape juice and wine. Additionally, the toxicity of OTA irradiated in water was tested. In aqueous solutions, more than 90% of the OTA wa...


Aflatoxins detoxification by gamma irradiation

Calado, Thalita; Abrunhosa, Luís; Verde, Sandra Cabo; Fernández-Cruz, María Luisa

[Excerpt] Mycotoxins are secondary toxic metabolites of filamentous fungi. Aflatoxins (AFs) are produced to Aspergillus species such as A. flavus and A. parasiticus. These fungi are ubiquitous in nature and usually found on agricultural commodities. Therefore, AFs are encountered in many important foodstuff, including wheat, rice, maize, peanuts, sorghum, pearl millet, spices, oilseeds, tree nuts and milk. Due ...


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