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Epidemiology, control and surveillance of Chagas disease - 100 years after its ...

Coura, José Rodrigues; Dias, João Carlos Pinto

Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Doenças Parasitárias. Rio de Janeiro, RJ, Brasil.; Fundação Oswaldo Cruz. Instituto de Pesquisas René Rachou. Belo Horizonte, MG, Brasil.; Chagas disease originated millions of years ago as an enzootic infection of wild animals and began to be transmitted to humans as an anthropozoonosis when man invaded wild ecotopes. While evidence of human infecti...

Date: 2019   |   Origin: Oasisbr

A serological, parasitological and clinical evaluation of untreated Chagas dise...

Assis, Girley Francisco Machado de; Diniz, Glaucia Alessio; Montoya, Roberto Araújo; Dias, João Carlos Pinto; Coura, José Rodrigues

The etiological treatment of Chagas disease is recommended for all patients with acute or recent chronic infection, but controversies remain regarding the benefit of chemotherapy and interpretations of the parasitological cure after etiological treatment. This study compares the laboratory and clinical evaluations of Chagas disease patients who were diagnosed 13 years earlier. Fifty-eight Chagas disease patient...

Date: 2014   |   Origin: Oasisbr

Clinical and laboratory status of patients with chronic Chagas disease living i...

Lana, Marta de; Lopes, Leonardo de Araújo; Martins, Helen Rodrigues; Bahia, Maria Terezinha; Assis, Girley Francisco Machado de

Twenty-eight Chagas disease patients (CD), 22 with the indeterminate clinical form (IND) and six with the cardiac or digestive form (CARD/DIG), were treated with benznidazole and underwent clinical and laboratorial analysis before (IND and CARD/DIG) and nine years after [patients after treatment (CDt), patients with the indeterminate clinical form at treatment onset (INDt) and with the cardiac or digestive form...

Date: 2014   |   Origin: Oasisbr

Etiological treatment during early chronic indeterminate Chagas disease incites...

Avelar, Renato Sathler; Avelar, Danielle Marchetti Vitelli; Massara, Rodrigo Lima; Lana, Marta de; Dias, João Carlos Pinto; Carvalho, Andréa Teixeira de

Pro-inflammatory immune response is usually associated with Chagas disease pathogenesis, but is also relevant to treatment effectiveness. Cross-sectional studies have suggested that this activated state may persist for years after therapeutic intervention. However, short-term longitudinal investigation has suggested that the Benznidazole treatment (Bz-treatment) leads to decreased immunological activation. In o...

Date: 2014   |   Origin: Oasisbr

Hemocultures for the parasitological diagnosis of human chronic Chagas' disease.

Chiari, Egler; Dias, João Carlos Pinto; Lana, Marta de; Chiari, Cléa de Andrade

With the purpose of standardization of an hemoculture technique presenting a higher positive rate in the parasitological diagnosis of chronic Chagas’ disease in patients with reactive serology (IFT, HA, CFT) the following schedule was used. Thirty ml of venous blood was collected with heparin and the plasma was separated by centrifugation (2.000 rpm/30'). The packed cells were washed with LIT medium or PBS whic...

Date: 2014   |   Origin: Oasisbr

Seroprevalence of chagas disease in schoolchildren from two municipalities of j...

Borges, Jaila Dias; Assis, Girley Francisco Machado de; Gomes, Lizziani de Vasconcelos; Dias, João Carlos Pinto; Pinto, Ildikô Delkim Miranda

Six years after the beginning of the epidemiological surveillance of Chagas disease in Berilo and José Gonçalves de Minas, Jequitinhonha Valley, MG, Brazil, a serological inquiry was performed to observe whether the transmission of this endemy was occurring in this area. A randomized sample of 1,412 children seven to 14 years old, was screened. Six asymptomatic children were found to be positive, leading to 0.4...

Date: 2014   |   Origin: Oasisbr

The Noble Enigma: Chagas' Nominations for the Nobel Prize

Coutinho, Marilia; Freire Junior, Olival; Dias, João Carlos Pinto; Coutinho, Marilia; Freire Junior, Olival; Dias, João Carlos Pinto

p. 123-129; Submitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2013-07-31T19:24:17Z No. of bitstreams: 1 444444444444.pdf: 639420 bytes, checksum: fb0bfa8dc9597df5e893758c36c91fdb (MD5); Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2013-11-16T12:50:35Z (GMT) No. of bitstreams: 1 444444444444.pdf: 639420 bytes, checksum: fb0bfa8dc9597df5e893758c36c91fdb (MD5); Made avail...

Date: 2013   |   Origin: Oasisbr


Seroprevalence of Chagas disease in schoolchildren from two municipalities of J...

Borges, Jaila Dias; Assis, Girley Francisco Machado de; Gomes, Lizziani Vasconcelos; Dias, João Carlos Pinto; Pinto, Ildikô Delkim Miranda

Six years after the beginning of the epidemiological surveillance of Chagas disease in Berilo and José Gonçalves de Minas, Jequitinhonha Valley, MG, Brazil, a serological inquiry was performed to observe whether the transmission of this endemy was occurring in this area. A randomized sample of 1,412 children seven to 14 years old, was screened. Six asymptomatic children were found to be positive, leading to 0.4...

Date: 2006   |   Origin: Oasisbr

Chagas disease in a community in Southeast Brazil: I. A serlogic follow-up stud...

Montoya, Roberto; Dias, João Carlos Pinto; Coura, José Rodrigues

A prevalência da infecção pelo Trypanosoma cruzi foi avaliada no município de Berilo, Minas Gerais, Brasil, no período de janeiro a julho de 1997. Uma amostra de 2.261 indivíduos foi estudada sorologicamente mediante o teste de imunofluorescência indireta em sangue coletado em papel de filtro. A taxa de prevalência foi de 18% no total da população estudada e 50% em pessoas da área rural maiores de 30 anos. A pe...

Date: 2003   |   Origin: Oasisbr

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