12 documents found, page 1 of 2
Increased Synaptic ATP Release and CD73-Mediated Formation of Extracellular Ade...
Dias, Liliana; Pochmann, Daniela; Lemos, Cristina; Silva, Henrique B.; Real, Joana I.; Gonçalves, Francisco Q.; Rial, Daniel; Gonçalves, NélioIncreased ATP release and its extracellular catabolism through CD73 (ecto-5'-nucleotidase) lead to the overactivation of adenosine A2A receptors (A2AR), which occurs in different brain disorders. A2AR blockade blunts mood and memory dysfunction caused by repeated stress, but it is unknown if increased ATP release coupled to CD73-mediated formation of extracellular adenosine is responsible for A2AR overactivatio...
Candida auris in Intensive Care Setting: The First Case Reported in Portugal
Henriques, João; Mixão, Verónica; Cabrita, Joana; Duarte, Tiago Isidoro; Sequeira, Tânia; Cardoso, Sofia; Germano, Nuno; Dias, Liliana; Bento, LuísCandida auris is an opportunistic human pathogen that has rapidly spread to multiple countries and continents and has been associated with a high number of nosocomial outbreaks. Herein, we report the first case of C. auris in Portugal, which was associated with a patient transferred from Angola to an ICU in Portugal for liver transplantation after a SARS-CoV-2 infection. C. auris was isolated during the course ...
Candida auris in intensive care setting: the first case reported in Portugal
Henriques, João; Mixão, Verónica; Cabrita, Joana; Duarte, Tiago Isidoro; Sequeira, Tânia; Cardoso, Sofia; Germano, Nuno; Dias, Liliana; Bento, LuísCandida auris is an opportunistic human pathogen that has rapidly spread to multiple countries and continents and has been associated with a high number of nosocomial outbreaks. Herein, we report the first case of C. auris in Portugal, which was associated with a patient transferred from Angola to an ICU in Portugal for liver transplantation after a SARS-CoV-2 infection. C. auris was isolated during the course ...
Cross-allergy between penicillins and cephalosporins: a paradigm shift
Dias, Liliana; Pedrosa, CláudiaAllergic reactions to beta-lactam antibiotics are the most common cause of allergic drug reactions. The incorrect diagnosis prevents patients from receiving a highly effective therapy. The potential cross-reactivity between penicillin and cephalosporin has very significant therapeutic implications. Penicillins and cephalosporins share a common beta-lactam ring and side chains. A number of studies indicate that ...
Cross-allergy between penicillins and cephalosporins: a paradigm shift
Dias, Liliana; Neves, ClaudiaAllergic reactions to beta-lactam antibiotics are the most common cause of allergic drug reactions. The incorrect diagnosis prevents patients from receiving a highly effective therapy. The potential cross-reactivity between penicillin and cephalosporin has very significant therapeutic implications. Penicillins and cephalosporins share a common beta-lactam ring and side chains. A number of studies indicate that ...
Crosstalk Between ATP-P2X7 and Adenosine A2A Receptors Controlling Neuroinflamm...
Dias, Liliana; Lopes, Cátia R.; Gonçalves, Francisco Q.; Nunes, Ana R.; Pochmann, Daniela; Machado, Nuno J.; Tomé, Ângelo R.; Agostinho, PaulaDepressive conditions precipitated by repeated stress are a major socio-economical burden in Western countries. Previous studies showed that ATP-P2X7 receptors (P2X7R) and adenosine A2A receptors (A2AR) antagonists attenuate behavioral modifications upon exposure to repeated stress. Since it is unknown if these two purinergic modulation systems work independently, we now investigated a putative interplay betwee...
Beyond advertising narratives: Josefinas and their storytelling products
Dias, Liliana; Dias, PatríciaIn the last few years, advertising narratives have become increasingly important. Facing an environment of fierce competition and communication overload, brands needed to reinvent their communication strategies, and stories became protagonists, particularly in the digital environment. This article addresses a new way of applying storytelling in marketing, which is using it to extend products. In our theoretical...
Pedobacter lusitanus sp. nov., isolated from sludge of a deactivated uranium mine
Covas, Cláudia; Caetano, Tânia; Cruz, Andreia; Santos, Tiago; Dias, Liliana; Klein, Guenter; Abdulmawjood, Amir; Rodriguez-Alcala, Luis M.Strain NL19(T) is a Gram-stain-negative, aerobic bacterium that was isolated from sludge of a deactivated uranium mine in Portugal. 16S rRNA gene sequence analysis revealed that strain NL19(T) is a member of the genus Pedobacter and closely related to the strains Pedobacter himalayensis MTCC 6384(T), Pedobacter cryoconitis DSM 14825(T), Pedobacter westerhofensis DSM 19036 (T) and Pedobacter hartonius DSM 19033(...
Presença de alterações vocais e autoperceção das mesmas em professores do 1º ci...
Souto, Adriana; Cartaxo, Daniela; Dias, Liliana; Meireles, Paula; Soares, Elsa; Mina, Sónia Pós deEstado de Arte: Os professores são uma classe profissional que apresenta prevalência de alterações vocais. Refere-se então a importância da prevenção e da intervenção atempada para evitar o desenvolvimento de patologias vocais. Sendo esta uma classe profissional de risco e na ausência de informação sobre esta temática na literatura, considera-se pertinente perceber a prevalência e incidência de alterações vocai...
Resistência ao fogo de vigas em madeira e secções em perfis em aço
Dias, Liliana; Teixeira, Simone; Fonseca, E.M.M.A incorporação de aço com a madeira tem sido uma aposta em muitos projetos industriais pelas consideráveis vantagens que traduzem. A utilização de modelos madeira-aço tem como vantagens o aumento da resistência ao fogo e a melhoria na capacidade mecânica dessas estruturas. Existem diferentes soluções inovadoras, em madeira e seus derivados, para construções correntes, estruturais, não estruturais e de reabilita...