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loysia citrodora extract as a chemopreventive agent against HPV16-induced lesio...

Medeiros-Fonseca, Beatriz; Faustino-Rocha, Ana I; Silva, Jessica; Pires, Maria João; Neuparth, Maria João; Vala, Helena; Vasconcelos-Nóbrega, Carmen

Aim: Aloysia citrodora has a long history of traditional use in treating various ailments. This study evaluated the in vivo chemopreventive efficacy and systemic toxicity of an extract of A. citrodora in a transgenic mouse model of HPV16 (human papillomavirus type 16)-induced cancer. Methods: The experiment involved six groups (n = 5): group 1 (G1, wild-type (WT), water), group 2 (G2, HPV, water), group 3 (G3, ...


Fracture characterization of human cortical bone under mode II loading using th...

Silva, FG; de Moura, MF; Dourado, N; Xavier, J; Pereira, FA; Morais, JJ; Dias, MI; Lourenço, PJ; Judas, F

Fracture characterization of human cortical bone under mode II loading was analyzed using a miniaturized version of the end-notched flexure test. A data reduction scheme based on crack equivalent concept was employed to overcome uncertainties on crack length monitoring during the test. The crack tip shear displacement was experimentally measured using digital image correlation technique to determine the cohesiv...


Mode I fracture characterization of human bone using the DCB test

Silva, FG; Moura, MF; Pereira, FA; Morais, JJ; Dias, MI; Lourenço, PJ; Judas, F

Purpose – Fracture characterization of human cortical bone under pure mode I loading was performed in this work. The purpose of this paper is to validate the proposed test and procedure concerning fracture characterization of human cortical bone under pure mode I loading. Design/methodology/approach – A miniaturized version of the double cantilever beam (DCB) test was used for the experimental tests. A data red...


Uma viagem psicológica pela migração

Dias, MI

Nas diferentes abordagens e linguagens sobre a migração, enfatiza-se a dimensão psicológica com um percurso pelas razões e circunstâncias da mesma, analisando a descontextualização do indivíduo, as roturas, o risco transcultural e o possível trauma migratório. O conceito de doença e vivência da doença são referidos bem como a noção de alteridade, a dimensão cultural na relação terapêutica e a técnica da descent...


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