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Introduction: Kaposi’s sarcoma (KS) is a rare angioproliferative neoplasm associated with human herpesvirus 8 infection, presenting as four subtypes: classic, endemic, iatrogenic, and epidemic. While well documented globally, comprehensive data on KS in Portugal remain scarce. The aim of this retrospective study was to provide a detailed analysis of KS cases diagnosed at Hospital Santa Maria, in Lisbon, between...
The use of subcutaneous and intramuscular progesterone injections for non-therapeutic purposes has become increasingly common in Africa, particularly in Angola, where weak regulation allows unsupervised use. We report the case of a 26-year-old Angolan woman who developed lipomembranous panniculitis after six months of daily subcutaneous progesterone injections for libido enhancement at a non-medical center. She...
Generalized pustular psoriasis (GPP) is a rare but severe inflammatory skin disease characterized by the eruption of widespread sterile pustules, often accompanied by systemic inflammation. Although GPP can coexist with plaque psoriasis, it is increasingly recognized as a distinct entity with unique clinicopathological, immunologic, and genetic features. The dysregulated IL-36 pathway, including mutations in th...
No abstract available
Parvovirus B19 (PvB19), the etiological agent of erythema infectiosum, can manifest in diverse clinical forms. This study underscores the virus’s capacity to mimic other diseases, as illustrated by the diagnostic challenges encountered across five cases. The first three cases correspond to an overlap of papulo-purpuric gloves and socks syndrome with petechial exanthema with periflexural and periorificial distri...
Lichen sclerosus (LS) is a chronic inflammatory skin condition characterized by progressive epidermal atrophy and hypopigmentation, usually affecting the anogenital area. Patients may also present with extragenital lesions,though only 6% of LS cases are isolated to extragenital skin. Extragenital lichen sclerosus (EGLS) can be localized or widespread. Given the rare nature of extragenital-only forms of LS, ther...
Cutaneous diseases in returning travelers encompass a wide spectrum of etiologies and often pose diagnostic challenges. We present the cases of a 50-year-old man and a 57-year-old woman who presented with a 3-month history of erythematous, ulcerated plaques with well-defined elevated borders and a necrotic center on the lower limbs that began 3 weeks after returning from vacation in Costa Rica. Cutaneous biopsy...