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Valorization of Solanum melongena L. crop by-products: phenolic composition and...

Añibarro-Ortega, Mikel; Dias, Maria Inês; Petrović, Jovana; Núñez, Sonia; Calhelha, Ricardo C.; Costa, Eduardo M.; Machado, M.; Pintado, Manuela

This study explored the valorization of post-harvest eggplant aerial parts as a sustainable source of value-added ingredients by investigating their phenolic composition and in vitro bioactive properties. HPLC-DAD-ESI/MSn analysis identified chlorogenic acid derivatives as the predominant phenolic compounds (53 % of the phenolic fraction), followed by O-glycosylated kaempferol and quercetin. The extract display...


Optimization of heat and ultrasound-assisted extraction of Eucalyptus globulus ...

Lima, Laíres; Pereira, Ana I.; Vaz, Clara B.; Ferreira, Olga; Dias, Maria Inês; Heleno, Sandrina A.; Calhelha, Ricardo C.; Barros, Lillian

The extraction of phenolic compounds from eucalyptus leaves was optimized using heat and ultrasound-assisted techniques, and the bioactive potential of the resulting extract was assessed. The independent variables, including time (t), solvent concentration (S), and temperature (T) or power (P), were incorporated into a fivelevel central composite design combined with Response Surface Methodology. Phenolic conte...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Nutrients, Phytochemicals, and In Vitro Biological Activities of Goldenberry (P...

Añibarro-Ortega, Mikel; Dias, Maria Inês; Petrović, Jovana; Mandim, Filipa; Núñez, Sonia; Soković, Marina; López, Víctor; Barros, Lillian; Pinela, José

This study provides a comprehensive characterization of Physalis peruviana L., covering the nutritional composition of the fruit and the phytochemical profiles and in vitro bioactive properties of berry and calyx extracts. The fresh fruit stood out as a source of dietary fiber (5.16 g/100 g) and is low in fat (0.49 g/100 g). A 100-g serving also contained notable amounts of ascorbic acid (32.0 mg), tocopherols ...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Chemical Characterization and Differential Lipid-Modulating Effects of Selected...

Amorim, Ricardo; Marques, Mário Pedro; Melim, Catarina; Varela, Carla; Sardão, Vilma A.; Teixeira, José; Dias, Maria Inês; Barros, Lillian

Côa Valley, located in the northeast of Portugal, harbors more than 500 medicinal plant species. Among them, four species stand out due to their traditional uses: Equisetum ramosissimum Desf. (hemorrhages, urethritis, hepatitis), Rumex scutatus L. subsp. induratus (Boiss. and Reut.) Malag. (inflammation, constipation), Geranium purpureum Vill., and Geranium lucidum L. (pain relief, gastric issues). Given their ...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Valorisation of pumpkin by-products: Chemical composition and bioactive propert...

Leichtweis, Maria G.; Molina, Adriana K.; Dias, Maria Inês; Calhelha, Ricardo C.; Pires, Tânia C.S.P.; Pavli, Ourania; Oliveira, Beatriz

This study evaluated the fruit by-products (peels, seeds, and fibrous strands) from 11 pumpkin genotypes cultivated in Greece aiming to valorize them as natural sources of bioactive compounds. Five compounds, including ( )-epicatechin and chicoric acid isomers, were identified in peels, while seeds and fibrous strands mainly contained ( )-epicatechin. Organic acids and tocopherols varied significantly among gen...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Application of encapsulated tomato by-product extract as a colorant in mascarpone

Molina, Adriana K.; Leichtweis, Maria G.; Machado, Manuela; Silva, Sara; Pintado, Manuela; Barreira, João C. M.; Dias, Maria Inês; Prieto, Miguel Á.

Agricultural by-products, often underutilized, represent a significant opportunity to obtain sustainable value-added products to develop new functional foods. In this context, the (typically discarded) aerial parts of tomato plants (Solanum lycopersicum L. var. cerasiforme), were studied as new sources of natural bioactive compounds, focusing the extraction and encapsulation (using spray drying with maltodextri...


Protective properties of the edible halophyte Carpobrotus edulis (L.) N.E.Br. t...

Oliveira, Daniela; Hayrapetyan, Ruzanna; Dias, Maria Inês; Barros, Lillian; Séverin, Isabelle; Custódio, Luísa; Chagnon, Marie-Christine; Oliveira, Rui

Carpobrotus edulis (L.) N.E.Br. is an edible halophyte native to South Africa, where it has been traditionally consumed as food, revealing its nutritional value, and used in the treatment of human diseases probably due to the accumulation of bioactive compounds such as polyphenols. These compounds have potential to display valuable biological activities that could bring several benefits to the human being, incl...


Effects of electron beam radiation on the phenolic composition and bioactive pr...

Madureira, Joana; Gonçalves, Inês; Cardoso, Jéssica; Dias, Maria Inês; Santos, Pedro M. P.; Margaça, Fernanda M. A.; Santos-Buelga, Celestino

Olive pomace is an agro-industrial waste product generated from the olive oil industry and constituted by bioactive compounds with potential applications in several industrial sectors. The purpose of this work was to evaluate the effects of electron beam (e-beam) radiation on olive pomace, specifically on phenolic compounds (by HPLC-DAD-ESI/MS) and the bioactive properties (antioxidant, antiproliferative, and a...


Insights into the phenolic composition and in vitro bioactivity of cardoon capi...

Mandim, Filipa; Pinela, José; Marcelino, Sandra; Barracosa, Paulo; Ivanova, Marija; Dias, Maria Inês; Soković, Marina; Celestino, Santos-Buelga

The capitulum constituents (stigma, corolla, bracts, pappus, and receptacle) of seven cardoon cultivars were studied for their polyphenolic composition and bioactive properties. Fifteen phenolic compounds were identified, secoiridoid, secoxyloganin, and apigenin-O-hexuronoside in higher concentrations. The bracts had the highest concentration of phenolic compounds, and the corolla had the greatest variety. The ...


Exploring the therapeutic potential of Quercus ilex acorn extract in papillomav...

Medeiros-Fonseca, Beatriz; Faustino-Rocha, Ana I.; Pires, Maria João; Neuparth, Maria João; Vala, Helena; Nóbrega, Carmen; Gouvinhas, Irene

Background and Aim: Papillomaviruses (PVs) infections have been documented in numerous animal species across different regions worldwide. They often exert significant impacts on animal health and livestock production. Scientists have studied natural products for over half a century due to their diverse chemical composition, acknowledging their value in fighting cancer. Acorns (Quercus ilex) are believed to have...


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