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Physiological implications of NTBI uptake by T lymphocytes

Pinto, J.; Arezes, J.; Dias, V.; Oliveira, S.; Vieira, I.; Costa, M.; Vos, M.; Carlsson, A.; Rikers, Y.; Rangel, M.; Porto, G.

In iron overload disorders a significant fraction of the total iron circulates in the plasma as low molecular weight complexes not bound to transferrin, known as non-transferrin-bound iron (NTBI). By catalyzing the formation of free radicals, NTBI accumulation results in oxidative stress and cellular damage, being a major cause of organ toxicity. NTBI is rapidly and preferentially cleared from circulation by th...


An AHP-based approach to credit risk evaluation of mortgage loans

Ferreira, F.; Santos, S.; Dias, V.

Mortgage loans for home purchase require careful analysis by all parties involved in the transaction, and credit-scoring is usually adopted to assist the decision process. From a credit institution standpoint, credit-scoring for mortgage loan risk evaluation becomes even more important in scenarios of economic turbulence and recession, primarily because of the severe restrictions imposed on credit availability ...

Date: 2014   |   Origin: Repositório ISCTE

Non-Transferrin-Bound Iron (NTBI) Uptake by T Lymphocytes: Evidence for the Sel...

Arezes, J.; Costa, M.; Vieira, I.; Dias, V.; Kong, X.; Fernandes, R.; Vos, M.; Carlsson, A.; Rikers, Y.; Porto, G.; Rangel, M.; Hider, R.; Pinto, J.

Iron is an essential nutrient in several biological processes such as oxygen transport, DNA replication and erythropoiesis. Plasma iron normally circulates bound to transferrin. In iron overload disorders, however, iron concentrations exceed transferrin binding capacity and iron appears complexed with low molecular weight molecules, known as non-transferrin-bound iron (NTBI). NTBI is responsible for the toxicit...


Successful management of Listeria monocytogenes pericarditis: case report and r...

Dias, V.; Cabral, S.; Anjo, D.; Vieira, M.; Antunes, N.; Carvalheiras, G.; Gomes, C.; Meireles, A.; Mendonça, T.; Torres, S.

Listeria monocytogenes, although an uncommon cause of illness in the general population, is feared principally because of the morbidity and mortality associated with CNS infections. Cardiovascular involvement with L. monocytogenes is very rare, and has been limited to endocarditis. We describe a case of Listeria pericarditis, which occurred in a 60-year-old man with Child-Pugh B cirrhosis who presented to the e...


PROGNÓSTICO A CURTO E LONGO PRAZO E FOLLOW-UP ANGIOGRÁFICO APÓS INTERVENÇÃO COR...

Vieira, M.; Dias, V.; Meireles, A.; Gomes, C.; Antunes, N.; Anjo, D.; Luz, A.; Dias, H.; Correia, A.; Pinto, R.; Silveira, J.; Sousa, P.


ENCERRAMENTO PERCUTÂNEO DE COMUNICAÇÃO INTERAURICULAR E FORAMEN OVALE PATENTE E...

Vieira, M.; Dias, V.; Meireles, A.; Gomes, C.; Antunes, N.; Anjo, D.; Guedes, R.; Oliveira, F.; Cabral, S.; Pereira, L.; Braga, P.; Cyrne-Carvalho, H.


HOME MONITORING SYSTEM EM DOENTES COM POLINEUROPATIA AMILOIDÓTICA FAMILIAR

Vieira, M.; Dias, V.; Meireles, A.; Gomes, C.; Antunes, N.; Anjo, D.; Roque, C.; Reis, H.; Lagarto, V.; Cyrne-Carvalho, H.; Torres, S.


Indução cirúrgica de caninos maxilares retidos

Frazão, S.; Dias, R.; Dias, V.; Silva, S.; Almeida, B.; Silva, A.

Date: 2008   |   Origin: Cadernos de Saúde

Prevalência de sisos inclusos na Clínica Universitária da UCP-CRB

Dias, R.; Dias, V.; Morais, J.; Lima, T.; Cardoso, A.; Correia, A.

Date: 2008   |   Origin: Cadernos de Saúde

Bioecologia da mosca da azeitona, Bactrocera oleae (Gmel.) em Santarém e contri...

Dias, V.; Godinho, Joana; Gong, H.; Rosa, A.; Silva, J.

Este trabalho pretende ser mais um contributo para o conhecimento da bioecologia da mosca da azeitona na região de Santarém complementando, assim, trabalhos já realizados na região (Rogado et al., 2001). Efectuou-se a monitorização do seu ciclo de vida durante 2 campanhas agrícolas (Junho de 2004 a Setembro de 2005) tendo sido seguido, em particular, o período de Inverno e Primavera, para melhor conhecimento da...


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