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A Case of Severe Cholestasis due to Hepatic AL Amyloidosis

Dias,Teresa; Ferreira,Diana; Moreira,Hélder; Nascimento,Telma; Santos,Arsénio; Carvalho,Armando

Introduction: Immunoglobulin light chain-associated amyloidosis results from extracellular tissue deposition of fibrilforming monoclonal immunoglobulin light chains, secreted by a clone of plasma cells. Although the liver is often involved histologically, most cases are clinically asymptomatic, and severe intrahepatic cholestasis as the primary manifestation of the disease is rare. Clinical Case: We report an u...

Date: 2019   |   Origin: SciELO Portugal
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