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Posterior reversible encephalopathy syndrome as a multiple sclerosis relapse mi...

Dias Da Costa, Mariana; Leal Rato, Miguel; Ferreira, João; Sá, João de; Santos, Monica

Posterior reversible encephalopathy syndrome is a rare syndrome involving the subcortical cerebral white matter. We describe the case of a 63-year-old male patient with relapsing remitting multiple sclerosis under interferon beta therapy and acute onset of atypical unilateral posterior reversible encephalopathy syndrome mimicking a relapse. This case highlights the importance of clinical suspicion for multiple ...


Recurrent syncope during migraine attacks

Dias Da Costa, Mariana; Nunes Vicente, Beatriz; Dourado Sotero, Filipa; Martins, Isabel Pavão

Migraine is a cyclic condition with attacks consisting mainly of intense headaches, sensory intolerance, and nausea or vomiting. Loss of consciousness during attacks is often attributed exclusively to a neurally mediated reflex to pain, although it may also be due to migraine's autonomic impairment, with cardiac conduction abnormalities, probably in relation to a degree of reduced sympathetic function. We repor...


Cerebral venous thrombosis following an immunoglobulin-E mediated anaphylactic ...

Dias Da Costa, Mariana; Alves, Pedro Nascimento; de Sousa, Diana Aguiar; Canhão, Patrícia

Background: Prothrombotic and pro-inflammatory states are known cerebral venous thrombosis risk factors. To date, two cases of venous thrombotic events after immunoglobulin-E mediated anaphylaxis have been reported. Herein, we describe the first case of cerebral venous thrombosis in close temporal relation with an immunoglobulin-E mediated anaphylactic event. Case description: A 51-year-old female presented wit...


Longitudinally extensive transverse myelitis with anti-myelin oligodendrocyte g...

Dias Da Costa, Mariana; Leal Rato, Miguel; Cruz, Diana; Valadas, Anabela; Antunes, Ana Patrícia; Albuquerque, Luísa

We report the case of a patient with symptoms of myelopathy following acute SARS-CoV-2 infection. MRI documented a longitudinally extensive transverse myelitis and further investigation was unremarkable with the exception of positivity for MOG-IgG in serum. This report extends the spectrum of post-COVID-19 neurological syndromes, and documents a very significant improvement to long-term oral corticosteroid ther...


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