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Endothelial dysfunction in cardiovascular diseases: mechanisms and in vitro models

Grego, Ana; Fernandes, Cristiana; Fonseca, Ivo; Dias-Neto, Marina; Costa, Raquel; Leite-Moreira, Adelino; Oliveira, Sandra Marisa; Trindade, Fábio

Endothelial cells (ECs) are arranged side-by-side to create a semi-permeable monolayer, forming the inner lining of every blood vessel (micro and macrocirculation). Serving as the first barrier for circulating molecules and cells, ECs represent the main regulators of vascular homeostasis being able to respond to environmental changes, either physical or chemical signals, by producing several factors that regula...


Correction to: Endothelial dysfunction in cardiovascular diseases: mechanisms a...

Grego, Ana; Fernandes, Cristiana; Fonseca, Ivo; Dias-Neto, Marina; Costa, Raquel; Leite-Moreira, Adelino; Oliveira, Sandra Marisa; Trindade, Fabio


High-dependency unit care after carotid endarterectomy for asymptomatic stenosis

Guimarães, Beatriz; Coelho, Andreia; Dias-Neto, Marina; Castro-Ferreira, Ricardo; Peixoto, João; Fernandes, Luís; Boal, Roberto; Machado, Marta

INTRODUCTION: Asymptomatic patients benefit from 3 to 6 hours of neurological and invasive blood pressure (BP) monitoring following carotid endarterectomy (CEA). Only a minority of patients will benefit from a prolonged stay in a high-dependency unit (HDU). The aim of this study was to externally validate previously described predictive variables of postoperative need for prolonged HDU stay. METHODS: To identif...

Date: 2025   |   Origin: Angiologia e Cirurgia Vascular

Jejunal Artery Aneurysm Exclusion With Immediate Vascular Reconstruction: A Cas...

Jácome, Filipa; Ramos, José; Teixeira, José; Cristino, Humberto; Dias-Neto, Marina

A 44 year-old previously healthy woman presented a persistent epigastric pain. Computed tomography revealed a saccular aneurysm with a diameter of 25x20 mm in the first jejunal artery and also a stenosis in the celiac trunk associated with median arcuate ligament syndrome, turning the hepatic perfusion dependent of the gastroduodenal artery flow. Through a midline laparotomy, celiac axis was exposed, and median...



Impact Of Open And Endovascular Caseload In Lower Limb Amputation In Portugal –...

Jácome, Filipa; Freitas, Alberto; Sampaio, Sérgio; Dias-Neto, Marina; Castro-Ferreira, Ricardo

Objectives: Effective revascularization is the cornerstone of limb salvage in chronic limb threatening ischemia. In recent years, less invasive endovascular revascularization techniques have supplanted surgical bypass as the primary mode of revascularization. The real impact of this transition is being increasingly questioned. This study aims to evaluate the endovascular evolution, and how it impacted the amput...


Imaging Red Flags In A Symptomatic Abdominal Aortic Aneurysm

Soares, Margaret; Jácome, Filipa; Ramos, José Fernando; Dias-Neto, Marina


Outcomes of elective and non-elective fenestrated-branched endovascular aortic ...

Dias-Neto, Marina; Vacirca, Andrea; Huang, Ying; Baghbani-Oskouei, Aidin; Jakimowicz, Tomasz; Mendes, Bernardo C.; Kolbel, Tilo; Sobocinski, Jonathan

Objective: To describe outcomes after elective and non-elective fenestrated-branched endovascular aortic repair (FB-EVAR) for thoracoabdominal aortic aneurysms (TAAAs). Background: FB-EVAR has been increasingly utilized to treat TAAAs; however, outcomes after non-elective versus elective repair are not well described. Methods: Clinical data of consecutive patients undergoing FB-EVAR for TAAAs at 24 centers (200...


Human immunodeficiency virus and carotid artery disease – single center experie...

Pereira-Neves, António; Pereira-Macedo, Juliana; Soares, Tiago; Duarte-Gamas, Luís; Jácome, Filipa; Nóbrega, Leandro; Dias-Neto, Marina

INTRODUCTION: People infected with the human immunodeficiency virus (HIV) - People living with HIV/AIDS (PLWHA) - seem to have an increased risk of incidence and prevalence of cardiovascular diseases, namely stroke of ischemic nature. Additional etiological mechanisms, in addition to aging, appear to lie in chronic virus-mediated inflammation as well as in antiretroviral therapy (ART). The aim of this study was...

Date: 2022   |   Origin: Angiologia e Cirurgia Vascular

The Use of Radiomic Analysis in Cardiovascular Diseases

Vieira Santos-Silva, Maria; Sousa-Nunes, Fábio; Fernando Teixeira, José; Leite-Moreira, Adelino; Barros, António; Dias-Neto, Marina

A The recent years of the cardiovascular medicine saw a rapid development of advanced imaging modalities. The new era of personalized medicine takes advantage of what can be interpreted from medical images, searching for underlying connections between image phenotyping and biological characteristics to support precise clinical decisions. The application of radiomics in cardiovascular imaging has lagged behind o...


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