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Nuclear magnetic resonance metabolomics of iron deficiency in soybean leaves

Lima, Marta R. M.; Diaz, Sílvia O.; Lamego, Inês; Grusak, Michael A.; Vasconcelos, Marta; Gil, Ana M.

Iron (Fe) deficiency is an important agricultural concern that leads to lower yields and crop quality. A better understanding of the condition at the metabolome level could contribute to the design of strategies to ameliorate Fe-deficiency problems. Fe-sufficient and Fe-deficient soybean leaf extracts and whole leaves were analyzed by liquid 1H nuclear magnetic resonance (NMR) and high-resolution magic-angle sp...


Can Biofluids Metabolic Profiling Help to Improve Healthcare during Pregnancy?

Graça, Gonçalo; Diaz, Sílvia O.; Pinto, Joana; Barros, António S.; Duarte, Iola F.; Goodfellow, Brian J.; Galhano, Eulália; Pita, Cristina

This paper describes a metabonomics study of 2nd trimester biofluids (amniotic fluid, maternal urine, and blood plasma), in an attempt to correlate biofluid metabolic changes with suspected/diagnosed fetal malformations (FM) and chromosomal disorders as well as with later occurring gestational diabetes mellitus (GDM), preterm delivery (PTD), and premature rupture of membranes (PROM). The global biochemical pict...


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