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cis-bis(N-benzoyl-N0 ,N0 -dibenzylthioureido) platinum(II) : synthesis, molecul...

Correa, Rodrigo de Souza; Oliveira, Katia Mara de; Pérez, Hiram; Stevens, Ana María Plutín; Cairo, Raúl Ramos; Mocelo, Raúl; Castellano, Eduardo Ernesto

In this paper, the title compound was synthesized from N-benzoyl-N′,N′-dibenzylthiourea ligand and potassium tetrachloroplatinate(II), and its interaction with human (HSA) and bovine (BSA) serum albumin was evaluated. Also, the crystal structure was determined from single-crystal X‐ray diffraction, confirming that the platinum atom is coordinated with two chelated N-benzoyl-N′,N′-dibenzylthiourea ligands in a d...

Date: 2020   |   Origin: Oasisbr

Structure/activity of PtII/N,N-Disubstituted-N’-acylthiourea complexes: Anti-tu...

Plutín, Ana M.; Alvarez, Anislay; Mocelo, Raúl; Ramos, Raúl; Sánchez, Osmar C.; Castellano, Eduardo E.; da Silva, Monize M.; Villarreal, Wilmer

Made available in DSpace on 2018-12-11T17:36:55Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-06-01. Added 1 bitstream(s) on 2019-10-09T18:33:12Z : No. of bitstreams: 1 S0103-50532018000601256.pdf: 1399196 bytes, checksum: 4adcb58edc86aa2a4ea4357033d86303 (MD5); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); The...

Date: 2018   |   Origin: Oasisbr

Palladium(II)/N,N-disubstituted-N′-acylthioureas complexes as anti-Mycobacteriu...

Plutín, Ana M.; Alvarez, Anislay; Mocelo, Raúl; Ramos, Raúl; Castellano, Eduardo E.; da Silva, Monize M.; Villarreal, Wilmer; Pavan, Fernando R. [UNESP]

Made available in DSpace on 2018-12-11T17:32:29Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-01-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); The new complexes of Pd(II) with N,N-disubstituted-N′-acylthioureas:[(1) [Pd(dppf)(N,N-dimethyl-N′-ben...

Date: 2018   |   Origin: Oasisbr

Anti-Mycobacterium tuberculosis activity of platinum(II)/N,N-disubstituted-N′-a...

Plutín, Ana M.; Alvarez, Anislay; Mocelo, Raúl; Ramos, Raúl; Castellano, Eduardo E.; Da Silva, Monize M.; Colina-Vegas, Legna

Made available in DSpace on 2018-12-11T17:26:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-01-01; Synthesis, characterization and anti-Mycobacterium tuberculosis assays of new platinum(II)/dppf/N,N-disubstituted-N′-acyl thiourea complexes with general formulae [Pt(dppf)(L)]PF6, [dppf = 1,1′-bis(diphenylphosphino)ferrocene; L = N,N-disubstituted-N′-acyl thioureas] is reported. The complexes were char...

Date: 2018   |   Origin: Oasisbr

Ru(II)-based complexes with N-(acyl)-N′,N′-(disubstituted)thiourea ligands : sy...

Correa, Rodrigo de Souza; Oliveira, Katia Mara de; Delolo, Fábio Godoy; Alvarez Hernández, Anislay; Mocelo, Raúl; Plutin, Ana M.

Four ruthenium(II)-based complexeswith N-(acyl)-N′,N′-(disubstituted)thiourea derivatives (Th)were obtained. The compounds, with the general formula trans-[Ru(PPh3)2(Th)(bipy)]PF6, interact with bovine serum albumin (BSA) and DNA. BSA-binding constants, which were in the range of 3.3–6.5 × 104 M−1, and the thermodynamic parameters (ΔG, ΔH and ΔS), suggest spontaneous interactions with this protein by electrosta...

Date: 2016   |   Origin: Oasisbr

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