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Docosahexaenoic acid inhibits Helicobacter pylori growth in vitro and mice gast...

Correia, Marta; Michel, Valérie; Matos, António A.; Carvalho, Patrícia; Oliveira, Maria J.; Ferreira, Rui M.; Dillies, Marie-Agnès; Huerre, Michel

H. pylori drug-resistant strains and non-compliance to therapy are the major causes of H. pylori eradication failure. For some bacterial species it has been demonstrated that fatty acids have a growth inhibitory effect. Our main aim was to assess the ability of docosahexaenoic acid (DHA) to inhibit H. pylori growth both in vitro and in a mouse model. The effectiveness of standard therapy (ST) in combination wit...


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