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Using Portuguese BRCA pathogenic variation as a model to study the impact of hu...

Andaluz, S; Zhao, B; Sinha, S; Lagniton, PN; Alpuim Costa, D; Ding, X; Brito, M; Wang, SM

Background: Admixture occurs between different ethnic human populations. The global colonization in recent centuries by Europeans led to the most significant admixture in human history. While admixture may enhance genetic diversity for better fitness, it may also impact on human health by transmitting genetic variants for disease susceptibility in the admixture population. The admixture by Portuguese global exp...

Date: 2024   |   Origin: Hospital de Cascais

Using Portuguese BRCA pathogenic variation as a model to study the impact of hu...

Andaluz, S; Zhao, B; Sinha, S; Lagniton, PN; Alpium Costa, D; Ding, X; Brito, M; Wang, SM

Background: Admixture occurs between different ethnic human populations. The global colonization in recent centuries by Europeans led to the most significant admixture in human history. While admixture may enhance genetic diversity for better fitness, it may also impact on human health by transmitting genetic variants for disease susceptibility in the admixture population. The admixture by Portuguese global exp...

Date: 2024   |   Origin: Saúde - CUF

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