Introduction: Scientific evidence regarding salivary gland cancer systemic treatment is limited and the therapeutic approach to locally advanced or metastatic disease is mainly based on consensus. This study aimed to evaluate treatment patterns and outcomes in patients with advanced salivary gland cancer.Methods: We conducted a retrospective cohort study in a comprehensive cancer center in Portugal, including a...
Introduction: Retroperitoneal soft tissue sarcomas have a wide range of histologic entities but they are frequently studied as a single disease. Being liposarcomas the most frequent histologic type, we’ve carried a retrospective analysis from a cohort of patients treated at a referral center to assess prognostic factors associated with demographic and therapeutic characteristics.Methods: A retrospective analysi...
O Regulamento Geral de Proteção de Dados (Regulamento (UE) 2016/679) avizinha-se como um normativo que vai mudar a realidade das organizações no contexto europeu.A adaptação das entidades constitui um desafio a ser levado a cabo por uma equipa interdisciplinar. Nesta fase inicial, em que as metodologias se encontram em desenvolvimento, esse processo tende a aplicar normativos e ferramentas existentes, concilian...
A aprendizagem ao longo da vida é um conceito que se encontra associado à evolução da sociedade como a conhecemos. As novas tecnologias da informação e comunicação tem contribuído para a criação e o desenvolvimento de várias ferramentas no âmbito da formação, educação e investigação, nas mais diversas áreas. Os mundos virtuais 3D são realidades alternativas onde as pessoas podem interagir entre si ou elementos ...
The development of biotechnology drugs represents one of the great advances in medical therapy and it was observed an exponential growth in its use. The resource to these drugs in Oncology and Hematology is no exception and it soon became an essential element of an integrated and directed therapy strategy. The expiry of the first biotechnology drugs patents has opened the door for the development and marketing ...
Neste estudo procura-se identificar as principais alterações introduzidas no âmbito da transformação, em curso, do Exército, em particular, quanto à incidência na organização das comunicações e sistemas de informação. Perante a situação da nova organização das comunicações e sistemas de informação, estudou-se o impacto da correspondente transformação e novos desafios utilizando a análise SWOT. Num primeiro pass...
Neutropenia and febrile neutropenia are common consequences of some cytotoxic chemotherapy regimens. This situation leads to modifications of the therapeutic regimen, conducting to either dose reduction or cycle delays. Granulocyte colony stimulating factors are commonly used to minimize chemotherapy cytotoxic effect on the granulocytic series. The objective of this study is to assess the available evidence in ...
Oncologic disease is one of the main causes of death in Portugal, as well as a high morbidity rate. Over the past few years, these diseases have been targeted with several strategies which aims at optimizing the use of available therapeutic and diagnostic options. Nevertheless, the amount of quantitative information available regarding the disease, patient profile, and treatment and monitoring practices is very...
Multiple sclerosis (MS) is a demyelinating disease that affects about one in 500 young Europeans. In order to test the previously proposed influence of the APOE and SCA2 loci on susceptibility to MS, we studied these loci in 243 Portuguese patients and 192 healthy controls and both parents of 92 patients. We did not detect any significant difference when APOE and SCA2 allele frequencies of cases and controls we...