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Exploring Innovations and Key Insights in Healthcare

On behalf of the Editorial Team of Scientific Letters, we are pleased to announce the publication of the third issue. The 2024 edition of Scientific Letters presents a diverse array of research that highlights significant advancements in health, dentistry, and clinical treatments.

The power of DNA and fingerprint databases

Background: Recent advancements in various scientific fields (e.g., next-generation DNA sequencing, AI-driven biometrics, rapid DNA, enhanced fingerprint systems, cloud-based digital forensics) resulted in the emergence of different branches within Forensic Sciences, which provide comprehensive support to the justice system [1-3]. The present work specifically focuses on two areas of criminalistics: Forensic Ge...

Bacterial load and dynamics: exploring their potential as biomarkers for postmo...

Background: Establishing the postmortem interval (PMI), the time since death, is vital in forensic investigations but remains challenging due to multiple factors like the cause of death, body location, and environmental conditions [1]. Traditional PMI estimation methods include Algor Mortis, Rigor Mortis, and Livor Mortis, along with complementary approaches from entomology, botany, and microbiology, though all...

Optimization and validation of an HPLC-DAD method for the identification of 14 ...

Background: Cannabis sp. plant has its origins in East Asia, where it was initially used for recreational and religious purposes. This plant encompasses hundreds of chemical compounds, including phytocannabinoids, terpenoids, and flavonoids. The cannabinoids of greatest medicinal interest are Δ9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD), which are present in the plant in their acid form [1]. Sativex® ...

Analysis of terpenes in cannabis by GC-MS: method development and its applicati...

Background:  In addition to cannabinoids, key bioactive compounds in cannabis, terpenes and terpenoids, also have therapeutic importance, potentially working synergistically through their entourage effect for the medicinal efficacy of this plant [1,2]. Besides their therapeutic advantages, they are also responsible for the characteristic aroma of numerous varieties of cannabis, ranging from citrus to woody...

The future of toxicology research in the era of artificial intelligence: the vi...

Toxicology, the great science of understanding the toxic effects of chemical substances on living organisms, is increasingly being integrated within the One Health framework – the holistic approach that recognizes the interconnectedness of human, animal, and ecosystem health [1,2]. The One Health concept advocates interdisciplinary collaboration among veterinarians, physicians, environmental...

MicroMundo@IUCS_CESPU (2022-2024): uncovering soil’s hidden treasures and its i...

Background: MicroMundo@IUCS_CESPU (MMIC) is a service-learning pedagogical approach allowing university/school students to expand their knowledge on soil biodiversity, antimicrobial resistance (AMR) and experimental sciences [1]. School students experience a real research project by processing soil samples and looking for potential antibiotic-producing microorganisms [2,3]. Objective: To evaluate past MMIC edit...

Unveiling the toxicological risks of synthetic cannabinoid smoking: a GC-MS-bas...

Background: Synthetic cannabinoids (SCs) are a significant class of new psychoactive substances (NPS) commonly consumed via smoking. This process generates pyrolysis byproducts, some of which may exhibit increased toxicity compared to their parent compounds. The structural diversity and rapid emergence of SCs and the use of different herbal products pose challenges in forensic toxicology, necessitating comprehe...

Development and validation of an HPLC-DAD analytical method for psilocybin and ...

Background: "Magic mushrooms", also known as hallucinogenic mushrooms, belong to the genus Psilocybe and contain tryptamines, especially psilocybin and psilocin, with potential medicinal benefits for mental health [1]. Psilocybin is usually found in higher concentrations than psilocin and both are present in dried mushrooms at a total concentration of approximately 0.5 to 1.5%. Psilocybe mushrooms are used for ...

O Início da Missão Forense de Transformar a Ciência em Justiça!