12 documents found, page 1 of 2

Imipenem-Relebactam Susceptibility in Enterobacterales Isolates Recovered from ...

Imipenem-relebactam is a novel β-lactam-β-lactamase inhibitor combination. We evaluated the in vitro activity of imipenem-relebactam and comparators against Enterobacterales clinical isolates recovered in 8 Spanish and 11 Portuguese intensive care units (ICUs) (SUPERIOR, 2016-2017; STEP, 2017-2018). Overall, 747 Enterobacterales isolates (378 Escherichia coli, 252 Klebsiella spp., 64 Enterobacter spp., and 53 o...

Invasive and Subcutaneous Infections Caused by Filamentous Fungi: Report from a...

Invasive fungal infections (IFI) have significantly increased over the past years due to advances in medical care for the at-risk immunocompromised population. IFI are often difficult to diagnose and manage, and can be associated with substantial morbidity and mortality. This study aims to contribute to understanding the etiology of invasive and subcutaneous fungal infections, their associated risk factors, and...

Psychogenic purpura – remembering a rare image

Recordando la parotiditis en la era del SARS-CoV-2

New 2019-Coronavirus (SARS-CoV-2) pandemic is presenting daily diagnostic challenges to emergency departments (ED) doctors, especially as an increasing number of atypical clinical presentations have been reported, including acute sialadenitis (most of parotid). We present a case of a 46-year-old obese caucasian woman, with no relevant medical history, that presented in ED with complaints suggesting parotitis, w...

Confronting Ceftolozane-Tazobactam Susceptibility in Multidrug-Resistant Entero...

Ceftolozane-tazobactam (C/T) is frequently used for infections caused by multidrug-resistant (MDR)-Enterobacterales isolates. Whole-genome sequencing (WGS, Illumina-Hiseq 4000/NovaSeq 6000, OGC, UK) was used to study the population structure, the resistome and the virulome of C/T-susceptible and -resistant MDR Escherichia spp. (n=30) and Klebsiella spp. (n=78) isolates, recovered from lower respiratory, intra-a...

Q Fever: an Emerging Reality in Portugal

Q fever is a zoonosis caused by Coxiella burnetii with worldwide distribution at the increasing expression in Europe and endemic in Portugal. It is transmitted by inhalation of aerosols containing spores, main reservoir being cattle, goats and sheep as by ingesting cottage cheese or unpasteurized milk. The majority of patients are asymptomatic; however, they may present with fever, atypical pneumonia, acute hep...

In Vitro Activity of Ceftolozane-Tazobactam Against Enterobacterales and Pseudo...

The STEP surveillance study was designed to increase knowledge about distribution of multidrug-resistant (MDR) Enterobacterales and Pseudomonas aeruginosa in Portugal, focusing on the intensive care unit (ICU). Antimicrobial susceptibility of common agents was also evaluated and compared with that of one of the latest therapeutic introductions, ceftolozane-tazobactam (C/T). Clinical isolates of Enterobacterales...

Direct application of the INNO-LiPA Rif.TB line-probe assay for rapid identific...

The INNO-LiPA Rif.TB assay for the identification of Mycobacterium tuberculosis complex strains and the detection of rifampin (RIF) resistance has been evaluated with 360 smear-positive respiratory specimens from an area of high incidence of multidrug-resistant tuberculosis (MDR-TB). The sensitivity when compared to conventional identification/culture methods was 82.2%, and the specificity was 66.7%; the sensit...

Chronic diarrhea as late complication of partial gastrectomy.

The authors present a clinical case of a forty-nine-year-old man admitted to hospital because of a seven month history of diarrhoea. The patient had been submitted to partial gastrectomy twenty-two years ago due to peptic ulcer. The analytic study was compatible with malabsorption syndrome. The colonoscopic and radiological studies revealed the existence of two fistulas between the gastric-stump, the small inte...

Multicenter study of isolated micro-organisms resistant to antimicrobials in 10...

In 1994, Microbiology Laboratories of ten Portuguese hospitals analysed isolated microorganisms found in blood and urine samples and studied antimicrobial susceptibilities of the most frequent bacterial pathogens. From 63780 blood samples, the most frequent were Staphylococcus spp. and from 69189 urine samples significant numbers of Escherichia coli, Enterococcus spp., Pseudomonas aeruginosa and Candida spp. we...