12 documents found, page 1 of 2

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Optimal Cutoffs for the Ratio of Arterial Oxygen Partial Pressure to Inspired O...

Pölkki, Anssi; Reinikainen, Matti; Rochwerg, Bram; Jung, Christian; Sendagire, Cornelius; Chaudhuri, Dipayan; Martin, Greg S.; Selander, Tuomas

Publisher Copyright: © 2025 The Author(s). Acta Anaesthesiologica Scandinavica published by John Wiley & Sons Ltd on behalf of Acta Anaesthesiologica Scandinavica Foundation.; BACKGROUND: The ratio of arterial oxygen partial pressure to fraction of inspired oxygen (PaO2/FiO2, hereafter P/F ratio) is a key component of the Sequential Organ Failure Assessment (SOFA) score. It reflects the severity of hypoxaemic r...


Association of Noradrenaline Dose With Mortality in Critically Ill Patients: a ...

Reinikainen, Matti; Delamarre, Louis; Blaser, Annika Reintam; Hollenberg, Steven M; Lobo, Suzana M; Rezende, Ederlon; Moreno, Rui; Rhodes, Andrew

Background: Noradrenaline is currently the first-line vasopressor in treatment of circulatory failure. Its dose reflects illness severity, and together with dopamine, dobutamine and adrenaline, it is used in the Sequential Organ Failure Assessment (SOFA) score to grade cardiovascular dysfunction. Over the years, noradrenaline use has increased and it has largely replaced dopamine. As part of the SOFA-2 update, ...


Intensive Care Medicine in Portugal

Moreno, Rui; Rhodes, Andrew; Rezende, Ederlon


Rationale and Methodological Approach Underlying the Development of the Sequent...

Moreno, Rui; Rhodes, Andrew; Ranzani, Otavio; Salluh, Jorge; Berger-Estilita, Joana; Coopersmith, Craig M.; Juffermans, Nicole P.; Laffey, John

Importance: The Sequential Organ Failure Assessment (SOFA) score was published in 1996 to describe organ dysfunction in critically ill adult patients in a readily quantifiable and sequential manner. Considerable changes have occurred over the last 3 decades in the use of organ support drugs and devices and in patient outcomes, necessitating revision of the score. Objectives: To develop definitions of organ dysf...



Intensive Care Unit Caseload and Workload and Their Association With Outcomes i...

Zajic, Paul; Engelbrecht, Teresa; Graf, Alexandra; Metnitz, Barbara; Moreno, Rui; Posch, Martin; Rhodes, Andrew; Metnitz, Philipp

Background: Too high or too low patient volumes and work amounts may overwhelm health care professionals and obstruct processes or lead to inadequate personnel routine and process flow. We sought to evaluate, whether an association between current caseload, current workload, and outcomes exists in intensive care units (ICU). Methods: Retrospective cohort analysis of data from an Austrian ICU registry. Data on p...


European Society of Intensive Care Medicine Guidelines on End of Life and Palli...

Kesecioglu, Jozef; Rusinova, Katerina; Alampi, Daniela; Arabi, Yaseen M; Benbenishty, Julie; Benoit, Dominique; Boulanger, Carole; Cecconi, Maurizio

The European Society of Intensive Care Medicine (ESICM) has developed evidence-based recommendations and expert opinions about end-of-life (EoL) and palliative care for critically ill adults to optimize patient-centered care, improving outcomes of relatives, and supporting intensive care unit (ICU) staff in delivering compassionate and effective EoL and palliative care. An international multi-disciplinary panel...


Outcomes of Patients Aged ≥80 Years with Respiratory Failure Initially Treated ...

Polok, Kamil; Fronczek, Jakub; Guidet, Bertrand; Artigas, Antonio; De Lange, Dylan W; Fjølner, Jesper; Leaver, Susannah; Beil, Michael; Sviri, Sigal

Background: Non-invasive ventilation (NIV) has been commonly used to treat acute respiratory failure due to COVID-19. In this study we aimed to compare outcomes of older critically ill patients treated with NIV before and during the COVID-19 pandemic. Methods: We analysed a merged cohort of older adults admitted to intensive care units (ICUs) due to respiratory failure. Patients were enrolled into one of two pr...


Erratum

Moreno, Rui; Martin, Greg S.


Sepsis without borders

Moreno, Rui; Martin, Greg S.


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