ABSTRACT: Pinus pinea nuts are commercial relevant Mediterranean edible forest nuts, with an increasing production and market value, whose industrial processing yields a lignocellulosic by-product, the pine nut shells, currently only used for combustion. Little research has been done on pine nut shells that could support a value-added application for this residue. This work studies for the first time the produc...
Pinus pinea nuts are commercial relevant Mediterranean edible forest nuts, with an increasing production and market value, whose industrial processing yields a lignocellulosic by-product, the pine nut shells, currently only used for combustion. Little research has been done on pine nut shells that could support a value-added application for this residue. This work studies for the first time the production of ol...
Excitatory/inhibitory imbalance has been suggested as a neurobiological substrate of the cognitive symptomatology in Autism Spectrum Disorder (ASD). Studies using magnetic resonance spectroscopy (MRS) attempted to characterize GABA and Glutamate brain levels in ASD. However mixed findings have been reported. Here, we characterize both neurochemical and physiological aspects of GABA system in ASD by implementing...
Neurofibromatosis type 1 (NF1) is associated with GABAergic dysfunction which has been suggested as the underlying cause of cognitive impairments. Previous intervention trials investigated the statins' effects using cognitive outcome measures. However, available outcome measures have led to inconclusive results and there is a need to identify other options. Here, we aimed at investigating alternative outcome me...
Introduction. To design more effective interventions, such as neurostimulation, for stroke rehabilitation, there is a need to understand early physiological changes that take place that may be relevant for clinical monitoring. We aimed to study changes in neurophysiology following recent ischemic stroke, both at rest and with motor planning and execution. Materials and Methods. We included 10 poststroke patient...
Objectives: Transcranial magnetic stimulation, in particular continuous theta burst (cTBS), has been proposed for stroke rehabilitation, based on the concept that inhibition of the healthy hemisphere helps promote the recovery of the lesioned one. We aimed to study its effects on cortical excitability, oscillatory patterns, and motor function, the main aim being to identify potentially beneficial neurophysiolog...
Annona cherimola Mill. seeds are a residue of the industrial processing of this fruit, for which, presently, there is no industrial application. They have a considerable amount of oil, which can be converted into biodiesel, but the remaining lignocellulosic fraction still needs relevant added-value valorization routes. In this work, the selective hemicelluloses removal by autohydrolysis was optimized aiming to ...