Made available in DSpace on 2022-04-28T19:50:37Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-02-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); We compared the parameters related to glucose homeostasis, and liver and muscle proteomes in fluorosis-susceptible (A/J; S) and fluorosis-resistant (129P3/J; R) mice in res...
Made available in DSpace on 2022-04-29T08:45:58Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-09-27; Although fluoride (F) is well-known to prevent dental caries, changes in cell processes in different tissues have been associated with its excessive exposure. Thus, this study aimed to evaluate the effects of F exposure on biochemical, proteomic, and genotoxic parameters of submandibular glands. Twenty ...
Made available in DSpace on 2022-04-29T08:46:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-01; Background Fluoride has become widely used in dentistry because of its effectiveness in caries control. However, evidence indicates that excessive intake interferes with the metabolic processes of different tissues. Thus, this study aimed to investigate the effects of long-term exposure to F on the paro...
Made available in DSpace on 2022-04-29T08:36:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-01; Objective: To study the proteomic alterations in the initial AEP after rinsing with CaneCPI-5, StN15 or Hb or their combination. Materials and methods: In five crossover phases, after prophylaxis, 10 volunteers in 5 consecutive days, rinsed (10 mL, 1 min) with the following solutions: deionized water (H...
Made available in DSpace on 2022-05-01T09:00:51Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-08-01; Background Pulmonary sequelae (PS) in patients with chronic paracoccidioidomycosis (PCM) typically include pulmonary fibrosis and emphysema. Knowledge of the molecular pathways involved in PS of PCM is required for treatment and biomarker identification. Methodology/Principal findings This non-concurren...
This work was supported by Pro-Reitoria ? de Pesquisa da UFPA (PROPESP, UFPA, Brazil), Brazilian National Council for Scientific and Technological Development (CNPq, Grant n. 435093/2018-5) and Coordena?ao ? de Aperfei?oamento de Pessoal de N?vel Superior (CAPES)- Finance Code 001.; Federal University of Par?. Institute of Biological Sciences. Laboratory of Functional and Structural Biology. Bel?m, PA, Brazil.;...
Made available in DSpace on 2021-06-25T10:35:09Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-11-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Objectives: To evaluate, in vivo: 1) proteomic alterations in the acquired enamel pellicle (AEP) after treatment with sugarcane-derived cystatin (CaneCPI-5), hemoglobin (H...
Made available in DSpace on 2021-06-25T11:03:06Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Fluoride (F) can induce changes in the expression of several liver proteins, most of them localized in the mitochondria and its effect is dose- and time-dependent. This study analyzed the effect of distinct F concentrations and exposure peri...
Made available in DSpace on 2021-06-25T11:03:07Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-02-10; Arterial stiffness, frequently associated with hypertension, is associated with disorganization of the vascular wall and has been recognized as an independent predictor of all-cause mortality. The identification of the molecular mechanisms involved in aortic stiffness would be an emerging target for hyp...
Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico ? Brasil (CNPq) and Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior Brasil (CAPES) - Finance Code 001; Universidade Federal do Par? (PROPESP, UFPA, Brazil); Federal University of Par?. Institute of Biological Sciences. Laboratory of Functional and Structural Biology. Bel?m, PA, Brazil.; Federal University of Par?. Institute of Biological ...