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How could nanobiotechnology improve treatment outcomes of anti-TNF-α therapy in...

Eder, Piotr; Zielinska, Aleksandra; Karczewski, Jacek; Dobrowolska, Agnieszka; Slomski, Ryszard; Souto, Eliana B.

Despite significant advances in therapeutic possibilities for the treatment of inflammatory bowel disease (IBD) in recent years, there is still a big room for improvement. In particular, biological treatment can induce not only clinical remission but also mucosal healing of the gastrointestinal tract. Among these therapeutic molecules, anti-tumor necrosis factor-alpha (anti-TNF-$\alpha$) antibodies were the fir...


Is the retinol-binding protein 4 a possible risk factor for cardiovascular dise...

Rychter, Anna Maria; Skrzypczak-Zielinska, Marzena; Zielinska, Aleksandra; Eder, Piotr; Souto, Eliana B.; Zawada, Agnieszka; Ratajczak, Alicja Ewa

Although many preventive and treatment approaches have been proposed, cardiovascular disease (CVD) remains one of the leading causes of deaths worldwide. Current epidemiological data require the specification of new causative factors, as well as the development of improved diagnostic tools to provide better cardiovascular management. Excessive accumulation of adipose tissue among patients suffering from obesity...


Primary humoral immune deficiencies: overlooked mimickers of chronic immune-med...

Malesza, Ida Judyta; Malesza, Michal; Krela-Kazmierczak, Iwona; Zielinska, Aleksandra; Souto, Eliana B.; Dobrowolska, Agnieszka; Eder, Piotr

In recent years, the incidence of immune-mediated gastrointestinal disorders, including celiac disease (CeD) and inflammatory bowel disease (IBD), is increasingly growing worldwide. This generates a need to elucidate the conditions that may compromise the diagnosis and treatment of such gastrointestinal disorders. It is well established that primary immunodeficiencies (PIDs) exhibit gastrointestinal manifestati...


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