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Control of endothelial quiescence by FOXO-regulated metabolites
Andrade, Jorge; Shi, Chenyue; Costa, Ana S. H.; Choi, Jeongwoon; Kim, Jaeryung; Doddaballapur, Anuradha; Sugino, Toshiya; Ong, Yu Ting; Castro, Marco(DFG, German Research Foundation) -Project-ID 75732319 -SFB 834, EXC 2026, project ID 390649896) DFG -Project-ID 268555672 -SFB 1213 MRC_MC_UU_12022/6 Cancer Center Support Grant 5P30CA045508; Endothelial cells (ECs) adapt their metabolism to enable the growth of new blood vessels, but little is known how ECs regulate metabolism to adopt a quiescent state. Here, we show that the metabolite S-2-hydroxyglutarate ...
Date: 2021
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Origin: Repositório Institucional da UNL