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Comparative pangenome analysis of capsulated Haemophilus influenzae serotype f ...

Gonzalez-Diaz, Aida; Carrera-Salinas, Anna; Pinto, Miguel; Cubero, Meritxell; van der Ende, Arie; Langereis, Jeroen D.; Domínguez, M. Ángeles

Haemophilus influenzae is an opportunistic pathogen adapted to the human respiratory tract. Non-typeable H. influenzae are highly heterogeneous, but few studies have analysed the genomic variability of capsulated strains. This study aims to examine the genetic diversity of 37 serotype f isolates from the Netherlands, Portugal, and Spain, and to compare all capsulated genomes available on public databases. Serot...


Assessment of trimethoprim-sulfamethoxazole susceptibility testing methods for ...

Sierra, Y.; Tubau, F.; González-Díaz, A.; Carrera-Salinas, A.; Moleres, J.; Bajanca-Lavado, P.; Garmendia, J.; Domínguez, M. Ángeles; Ardanuy, C.

To compare the determinants of trimethoprim-sulfamethoxazole resistance with established susceptibility values for fastidious Haemophilus spp., to provide recommendations for optimal trimethoprim-sulfamethoxazole measurement. We collected 50 strains each of Haemophilus influenzae and Haemophilus parainfluenzae at Bellvitge University Hospital. Trimethoprim-sulfamethoxazole susceptibility was tested by microdilu...


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