BACKGROUND: Asthma and Allergic Rhinitis (AR) are two chronic inflammatory diseases that are often concomitant. The Control of Allergic Rhinitis and Asthma Test (CARAT) was developed to evaluate the control of these diseases from the patients' perspective. Its performance in asthma patients without AR has not been previously studied. AIM: To test the hypothesis that CARAT can be used to assess asthma control in...
Tuberculosis is still one of the most important infectious diseases worldwide. Although human cases due to Mycobacterium bovis, the aetiological agent of bovine tuberculosis (bTB), considerably decreased in most industrialized countries, the possible zoonotic health hazard and the considerable economic losses it brings justify significant efforts to eradicate the disease in several countries. In Portugal, altho...
Bovine tuberculosis (bTB) prevalence has generally been decreasing for several years in Portugal due to an ongoing UE funded eradication programme. Nevertheless, new outbreaks have been intermittently recorded in bTB free herds, especially in two Eastern regions of Portugal (Beira Interior and Portalegre District part of Alentejo region), with no evident explanation referred in official epidemiological surveys....
Background: Economic evaluations help health authorities facing budget constraints. This study compares the health-related quality of life (HRQOL) and costs in patient subgroups on haemodialysis (HD) and renal transplantation (KT). Methods: In a prospective study with follow-up of 1-3 years, we performed a costutility analysis of KT vs. HD, adopting a lifetime horizon. A societal perspective was taken. Costs fo...
During five years (2002-2007), 295 MTC animal isolates, representing 25% of the total isolations from the bovine TB national eradication programme, were genotyped by spoligotyping and MIRU-VNTR typing. Main purposes were to assess the discriminatory power of different typing techniques and their usefulness for the Portuguese epidemiological scenario, to confirm transmission hypothesis between different cattle h...
BACKGROUND: The intensive requirement of organs for transplantation generates the need for higher rates of donation. METHODS: Using the national database of diagnosis-related groups for 2006, the global annual 2006 in-hospital mortality of 34 hospitals with organ-retrieval schemes was evaluated. Potential donors were estimated excluding patients aged <1 year or >70 years and presenting International Classificat...
Introduction: The clinical importance of humoral-mediated acute rejection has been progressively recognised. Early recognition and treatment with plasmapheresis and intravenous immunoglobulin have recently improved short term prognosis. Case report: In this report we describe the clinical features of three 2nd transplant patients developing severe acute humoral rejection during the first week post-transplant wh...