Aim: To develop the first Ophthalmology joint guidelines with Paediatric Rheumatology with recommendations on the screening, monitoring and medical treatment of juvenile idiopathic arthritis-associated uveitis (JIA-U), endorsed by the Portuguese Society of Ophthalmology (SPO). Methods: A systematic literature review was conducted to include publications up to July 14th 2020, with no language restrictions, in or...
AIM: To evaluate and compare the quality of life of patients submitted to XEN® implant or trabeculectomy and the relationship with potentially involved variables. METHODS: A cross-sectional study of patients with advanced open-angle glaucoma who underwent implantation of XEN® (group 1) and trabeculectomy (group 2) between October 2015 and February 2017. The studied variables were: age, gender, follow-up time, n...
Primary angle closure occurs as a result of crowded anterior segment anatomy, causing appositional contact between the peripheral iris and trabecular meshwork, thereby obstructing aqueous outflow. Several studies highlight the role of the crystalline lens in its pathogenesis. The objective of this work is to compare the long-term efficacy of phacoemulsification versus laser peripheral iridotomy (LPI) in the man...
Introdução: Uma complicação das doenças oculares inflamatórias é a neovascularização coroideia (NVC). Apesar de ser rara, é uma causa importante de perda de visão nestes doentes. As opções terapêuticas incluem, além do tratamento dirigido à doença inflamatória, a fotocoagulação a LASER, terapia fotodinâmina com verteporfina (TFD) e, mais recentemente, agentes farmacológicos anti-VEGF. Objectivo: Analisar uma sé...
Objectivo: Avaliar os resultados clínicos nos doentes submetidos a implante de válvula de Ah- med no serviço de Oftalmologia do Centro Hospitalar de Lisboa Central, EPE, entre Janeiro de 2010 e Junho de 2012. Material e Métodos: Estudo retrospectivo em que 39 doentes (44 válvulas) foram incluídos. Os critérios de inclusão compreenderam o diagnóstico de glaucoma refractário à terapêutica máxi- ma to...
Introdução: A toxoplasmose ocular pode manifestar-se sob a forma primária ou recorrente, sendo o pico de incidência da doença manifesta entre a 2a e a 4a década de vida. Apesar de tradi- cionalmente associada à fase aguda da infecção por Toxoplasma gondii, a toxoplasmose ocular primária também pode ocorrer na fase crónica da doença sistémica. Objectivos: relato de 3 casos clínicos e revisão da l...
Objectivo: Analisar e caracterizar uma amostra de doentes de uma consulta de inflamação ocular. Material e Métodos: Análise retrospectiva de 503 consultas realizadas por um clínico entre 1 de Agosto de 2012 e 31 de Agosto de 2013 no Centro Hospitalar de Lisboa Central com recurso aos respectivos processos clínicos. Na análise da casuística da consulta foram incluídos 151 doentes. Desses, 24 padeciam de doenças ...
Previous work showed the existence of ecotoxicity of water samples from the Alqueva reservoir due to the presence of the herbicides atrazine, simazine, terbuthylazine and metolachlor. In the present study we examine the effects of these herbicides singly and as binary mixtures on the growth rate of the microalgae Pseudokirchneriella subcapitata. Usually, the toxicity of mixtures is evaluated in relation to the ...
In the last decades biomarkers have been widely used for the assessment of effects and/or exposure to environmental contaminants, but to our knowledge few data has been published for isopod species. Along with biomarkers the quantification of energy reserves has also been used to evaluate organisms' energetic budget. Enzymatic biomarkers can also be useful to understand chemicals/stress modes of action. The aim...
Studies investigating the use of biomarkers in pesticide risk assessment have greatly increased in recent years; however, issues concerning the ecological meaning of enzymatic responses have proved controversial. Ideally a good biomarker response should be modulated by the environmental contaminants alone and demonstrate a predictable behavior towards certain types of toxins. As these premises are rarely observ...