10 documents found, page 1 of 1

Gelidium corneum and its solid by-product from agar extraction are sources of h...

The red alga Gelidium corneum is commonly harvested for agar extraction, producing significant biomass residue that remains underutilized. Gelidium corneum and its residue represent promising sources of high-value compounds, including lipid ingredients, encompassing omega-3 and omega-6 polyunsaturated fatty acids, with potential applications in foods and cosmetics. Algae lipids are quite diverse and complex, ho...

Water-Soluble Saccharina latissima Polysaccharides and Relation of Their Struct...

Brown macroalgae are an important source of polysaccharides, mainly fucose-containing sulphated polysaccharides (FCSPs), associated with several biological activities. However, the structural diversity and structure-function relationships for their bioactivities are still undisclosed. Thus, the aim of this work was to characterize the chemical structure of water-soluble Saccharina latissima polysaccharides and ...

Mitochondrial Fatty Acid β-Oxidation Disorders: From Disease to Lipidomic Studi...

Fatty acid oxidation disorders (FAODs) are inborn errors of metabolism (IEMs) caused by defects in the fatty acid (FA) mitochondrial β-oxidation. The most common FAODs are characterized by the accumulation of medium-chain FAs and long-chain (3-hydroxy) FAs (and their carnitine derivatives), respectively. These deregulations are associated with lipotoxicity which affects several organs and potentially leads to l...

Mitochondrial fatty acid β-oxidation disorders: from disease to lipidomic studi...

Fatty acid oxidation disorders (FAODs) are inborn errors of metabolism (IEMs) caused by defects in the fatty acid (FA) mitochondrial β-oxidation. The most common FAODs are characterized by the accumulation of medium-chain FAs and long-chain (3-hydroxy) FAs (and their carnitine derivatives), respectively. These deregulations are associated with lipotoxicity which affects several organs and potentially leads to l...

Chemical characterization and cytotoxic potential of an ellagitannin-enriched f...

The hepatocellular carcinoma, a primary malignancy of the liver, has a very poor prognosis and a lower survival rate. Moreover, the inefficacy of conventional therapies emphasizes the importance of discovering new bioactive compounds. Several studies clearly state that plant-derived polyphenols, namely ellagitannins, have several health benefits. Fragaria vesca leaves contain high amounts of polyphenols, being ...

Characterization of nitrophospholipid-peptide covalent adducts by electrospray ...

Lipids are well‐known targets of reactive nitrogen species and this reaction leads to the formation of nitrated lipids that have been associated with anti‐inflammatory and cytoprotective effects. Nitro‐fatty acids (NO2‐FA) are highly electrophilic compounds that can form covalent adducts with proteins, leading to the formation of lipoxidation adducts, which modulate the protein structure and function. Nitrated ...

Valorization of Lipids from Gracilaria sp. through Lipidomics and Decoding of A...

The lipidome of the red seaweed Gracilaria sp., cultivated on land-based integrated multitrophic aquaculture (IMTA) system, was assessed for the first time using hydrophilic interaction liquid chromatography-mass spectrometry and tandem mass spectrometry (HILIC-MS and MS/MS). One hundred and forty-seven molecular species were identified in the lipidome of the Gracilaria genus and distributed between the glycoli...

Decoding bioactive polar lipid profile of the macroalgae Codium tomentosum from...

Biotechnological applications of marine macroalgae have gained new interest due the added-value of their chemical constituents. This is the case of glycerolipids, phospholipids and glycolipids that display several commercial applications in food, pharmaceutical and cosmetic industries. This study is the first report on the isolation and characterization of the polar lipids of Codium tomentosum originating from ...

Lipidomics as a new approach for the bioprospecting of marine macroalgae: unrav...

Marine macroalgae, or seaweeds, have been used for direct human consumption, as additives in the food industry, and as fertilizers in agriculture. The fatty acid composition of several species of macroalgae has been extensively studied, considering their nutritional value and for phylogenetic characterization. However, the polar lipid components of macroalgae,which include compoundswith important nutraceutical ...

Molecular insights into mitochondrial dysfunction in cancer-related muscle wasting