3 documents found, page 1 of 1
Genomic analysis of two novel bacteriophages infecting Acinetobacter beijerinck...
Gomes, Marta Teresa Silva; Domingues, Rita Alexandra Carpinteiro; Turner, Dann; Oliveira, Hugo Alexandre MendesBacteriophages are the most diverse genetic entities on Earth. In this study, two novel bacteriophages, nACB1 (Podoviridae morphotype) and nACB2 (Myoviridae morphotype), which infect Acinetobacter beijerinckii and Acinetobacter halotolerans, respectively, were isolated from sewage samples. The genome sequences of nACB1 and nACB2 revealed that their genome sizes were 80,310 bp and 136,560 bp, respectively. Compa...
Proteínas imunogénicas contra A. baumannii: recurso para combater multirresistê...
Gomes, Marta; Domingues, Rita Alexandra Carpinteiro; Fraga, Alexandra Gabriel; Oliveira, Hugo Alexandre MendesAcinetobacter baumannii é um bactéria nosocomial e multirresistente, considerada pela da Organização Mundial da Saúde (OMS) como prioridade crítica para o desenvolvimento de novas estratégias antibacterianas.A imunização é uma estratégia eficiente para prevenir infeções, como por exemplo, por A. baumannii. As vacinas à base de proteínas têm vantagens sobre vacinas vivas, atenuadas ou inativas, uma vez que têm a...
Characterization of novel Acinetobacter baumannii phage-derived depolymerases w...
Domingues, Rita Alexandra CarpinteiroAcinetobacter baumannii is a pathogenic bacterium and is the major cause of nosocomial infections in hospital environment. Treatment of A. baumannii infections with antibiotics is extremely difficult due to their multi-resistance antibiotics. Moreover, most A. baumannii strains carry a capsular polysaccharide that is considered its main virulence factor, and a high variety of capsular types are produced by this...