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Enantiomeric biodistribution and toxicity of 3-chloromethcathinone (3-CMC) in W...

Langa, Ivan; Rocha-Pereira, Carolina; Milhazes, Nuno; Dias da Silva, Diana; Domingues, Susana; Silva, Paula; Barbosa, Joana; Faria, Juliana

Background: There has been a surge in global attention to New Psychoactive Substances (NPS) [1]. Synthetic cathinones stand out as a widely consumed NPS class. Notably, 3-chloromethcathinone (3-CMC) accounted for over 34% of NPS seizures in 2021 [2], which underscores concerns regarding its consumption and health effects. Of note, 3-CMC is chiral and mostly sold as a racemate. As human metabolism and pharm...

Date: 2024   |   Origin: Scientific Letters

Enantiomeric biodistribution and toxicity of 3-chloromethcathinone (3-CMC) in W...

Langa, Ivan; Rocha-Pereira, Carolina; Milhazes, Nuno; Silva, Diana Dias da; Domingues, Susana; Silva, Paula; Barbosa, Joana; Faria, Juliana

There has been a surge in global attention to New Psychoactive Substances (NPS) [1]. Synthetic cathinones stand out as a widely consumed NPS class. Notably, 3-chloromethcathinone (3-CMC) accounted for over 34% of NPS seizures in 2021 [2], which underscores concerns regarding its consumption and health effects. Of note, 3-CMC is chiral and mostly sold as a racemate. As human me-tabolism and pharmacological effec...


Bichectomia: bola de Bichat em foco

Domingues, Susana

A cirurgia de bichectomia consiste na remoção do Corpo Adiposo da Bochecha e tem tido sucesso no âmbito das intervenções cirúrgicas orais, contribuindo para a melhoria estética da face, para a harmonia do sorriso e tem sido ainda utilizada com o intuito de reconstruir defeitos maxilares, defeitos no palato duro e mole, rebordo alveolar, bochecha e fossa tonsilar/amigdalina. O presente estudo objetivo explorar o...


Abdominal Wall Hernias. Organize to Improve

Neto, António José; Magalhães, Carlos; Domingues, Susana; Seca, Manuel Jorge

The Ambulatory Surgery Unit of Santo António Hospital, by delegation of the Portuguese Society of Surgery’s Chapter of Abdo- minal Wall, undertook an appreciation of “state of the art” practice in what concerns surgical treatment of abdominal wall hernias in Portugal. This was carried out by the National Hospital Inquiry. All Portuguese Public Hospitals were asked to participate in the corresponding questionnai...

Date: 2010   |   Origin: Revista Portuguesa de Cirurgia

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