25 documents found, page 1 of 3
HLA-G genetic diversity and evolutive aspects in worldwide populations
Castelli, Erick C. [UNESP]; de Almeida, Bibiana S.; Muniz, Yara C. N.; Silva, Nayane S. B. [UNESP]; Passos, Marília R. S. [UNESP]Made available in DSpace on 2022-04-29T08:46:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-12-01; HLA-G is a promiscuous immune checkpoint molecule. The HLA-G gene presents substantial nucleotide variability in its regulatory regions. However, it encodes a limited number of proteins compared to classical HLA class I genes. We characterized the HLA-G genetic variability in 4640 individuals from 88 di...
Undifferentiated Spondyloarthropathies in Brazilians: Importance of HLA-B27 and...
Sampaio-Barros, Percival D.; Conde, Roseneide A.; Donadi, Eduardo A.; Kraemer, Maria Helena S.; Persoli, Ligia; Coimbra, Ibsen B.Made available in DSpace on 2022-04-29T08:42:53Z (GMT). No. of bitstreams: 0 Previous issue date: 2003-12-01; Objective. To analyze the profile of the HLA-B27 and B7 cross-reactive group (CREG) alleles and the role of these markers in disease characterization and progression in patients with undifferentiated spondyloarthropathies (uSpA). Methods. A total of 80 patients with a diagnosis of uSpA (40 HLA-B27 posit...
KIR2DL4 genetic diversity in a Brazilian population sample: implications for tr...
Weiss, Emiliana [UNESP]; Andrade, Heloisa S. [UNESP]; Lara, Juliana Rodrigues [UNESP]; Souza, Andreia S. [UNESP]; Paz, Michelle A. [UNESP]Made available in DSpace on 2021-06-25T10:53:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-06-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); KIR2DL4 is an important immune modulator expressed in natural killer cells; HLA-G is its main ligand. We have characterized the KIR2DL4 genetic diversity by considering the promoter, all exons, and all introns in a highly admixed Brazilian p...
Peripheral spectrum neurological disorder after arbovirus infection is associat...
Sonon, Paulin; Collares, Cristhianna V.A.; Ferreira, Maria Lúcia Brito; Almeida, Renata Santos; Sadissou, Ibrahim; Cordeiro, Marli TenórioMade available in DSpace on 2021-06-25T10:58:51Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-08-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação Oswaldo Cruz; Introduction: Non-classical class I human leukocyte antigens (HLA) molecules are known to modulate the function of cytotoxic cells (NK and T C...
Human leukocyte antigen (HLA)-F and -G gene polymorphisms and haplotypes are as...
Sonon, Paulin; Tokplonou, Léonidas; Sadissou, Ibrahim; M'po, Kuumaaté K.G.; Glitho, Sonya S.C.; Agniwo, Privat; Ibikounlé, MoudachirouMade available in DSpace on 2021-06-25T11:03:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-08-01; Institut de Recherche pour le Développement; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Background: Little attention has been devoted to the role of the immunoregulatory HLA-E/-F/−G genes in malaria. We evalu...
Expression of the nonclassical HLA-G and HLA-E molecules in laryngeal lesions a...
Silva, Tarsia G.; Crispim, Janaina C. O.; Miranda, Fabiana A.; Hassumi, Marcela K.; Mello, Julia M. Y. de; Simoes, Renata T.; Souto, FranciscoMade available in DSpace on 2020-12-10T19:01:04Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-12-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Introduction: HLA-G and HLA-E are two nonclassical class I molecules, which have been well recognized as modulators of innate and adaptive immune responses, and the express...
HLA-G AND HLA-E VARIABLE SITES ARE ASSOCIATED WITH SUSCEPTIBILITY TO P. FALCIPA...
Sonon, Paulin; Tokplonou, Leonidas; Sadissou, Ibrahim; M'po, Kuumaate K.; Glitho, Sonya S.; Ibikounle, Moudachirou; Paz, Michelle Almeida da [UNESP]Made available in DSpace on 2020-12-10T19:37:46Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-09-01; Univ Sao Paulo, FMRP, Ribeirao Preto, Brazil; Univ Paris 05, Sorbonne, IRD, MERIT, Paris, France; Univ Abomey Calavi, Dept Zool, Cotonou, Benin; Sao Paulo State Univ UNESP, Sch Med, Dept Pathol, Botucatu, SP, Brazil; Fac Sci Sante, Ctr Etud & Rech Paludisme Associe Grossesse & Enf, Cotonou, Benin; Univ ...
Hla-C genetic diversity and evolutionary insights in two samples from Brazil an...
Souza, Andreia S. [UNESP]; Sonon, Paulin; Paz, Michelle A. [UNESP]; Tokplonou, Léonidas; Lima, Thálitta H. A. [UNESP]; Porto, Iane O. P. [UNESP]Made available in DSpace on 2020-12-12T02:19:59Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Human leukocyte antigen-C (HLA-C) is a classical HLA class I molecule that binds and presents peptides to cytotoxic T lymphocytes in the cell surface. HLA-C has a dual function because it also interacts with Killer-cell immunoglobulin-like receptors (KIR) receptors expressed in natural killer and T cell...
HLA-G, -E and -F regulatory and coding region variability and haplotypes in the...
Sonon, Paulin; Sadissou, Ibrahim; Tokplonou, Léonidas; M'po, Kuumaaté K.G.; Glitho, Sonya S.C.; Agniwo, Privat; Ibikounlé, MoudachirouMade available in DSpace on 2019-10-06T16:48:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-12-01; HLA-G/E/F genes exhibit immunomodulatory properties and are expressed in placenta. Little attention has been devoted to the study of these genes in sub-Saharan African populations, which are yet the most diverse. To fill this gap, we evaluated the complete gene variability, approximately 5.1 kb for HLA-...
HLA-F displays highly divergent and frequent haplotype lineages associated with...
Buttura, Renato V. [UNESP]; Ramalho, Jaqueline [UNESP]; Lima, Thálitta H.A. [UNESP]; Donadi, Eduardo A.; Veiga-Castelli, Luciana C.Made available in DSpace on 2019-10-06T15:22:53Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-02-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); HLA-F is one of the most conserved loci among the HLA gene family. The exact function of HLA-F is stil...