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MediMARE - Mediation in Maritime Disputes / Book of Abstracts - Final Symposium

Lopes, Dulce; Borges, Fernando Vannier dos Santos; Donato, Roberta

Date: 2023   |   Origin: Estudo Geral - Universidade de Coimbra
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GABA release by basket cells onto Purkinje cells, in rat cerebellar slices, is ...

Donato, Roberta; Rodrigues, Ricardo J.; Takahashi, Michiko; Tsai, Ming Chi; Soto, David; Miyagi, Kana; Villafuertes, Rosa Gomez; Cunha, Rodrigo A.

In many brain regions, Ca2+ influx through presynaptic P2X receptors influences GABA release from interneurones. In patch-clamp recordings of Purkinje cells (PCs) in rat cerebellar slices, broad spectrum P2 receptor antagonists, PPADS (30 [mu]M) or suramin (12 [mu]M), result in a decreased amplitude and increased failure rate of minimal evoked GABAergic synaptic currents from basket cells. The effect is mimicke...

Date: 2008   |   Origin: Estudo Geral - Universidade de Coimbra
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