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Assessment of Lactobacillus crispatus´ role in vaginal infections: friend or foe?

Gaspar, C.; Rolo, J.; Vieira, Luís; Donder, G.; Martinez-de-Oliveira, J.; Palmeira-de-Oliveira, A.

Lactobacillus spp. are the most prevalent microorganisms in the vaginal milleu. Several probiotic mechanisms have been associated with Lactobacillus, but the most relevant one is lactate production – resulting in a low pH value, typical of the healthy vagina. However, its pathogenic state is still unknown. We aim to elucidate the role of a commensal vaginal microorganism, Lactobacillus crispatus, in vaginal inf...


Role of Lactobacillus crispatus in vaginal infections: insights from metagenomi...

Gaspar, C.; Rolo, J.; Vieira, Luís; Donder, G.; Martinez-de-Oliveira, J.; Palmeira-de-Oliveira, A.

Objective: Lactobacillus spp. constitute the most prevalent bacterial microorganism in the vaginal milleu. Several probiotic mechanisms have been associated with Lactobacillus, but the most relevant one is lactate production – resulting in a low pH value, typical of the healthy vagina. We aim to elucidate the role of a native vaginal microorganism, Lactobacillus crispatus, in vaginal infections. Methods: Twenty...


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