3 documents found, page 1 of 1
Domain-dependent evolution explains functional homology of protostome and deute...
Peng, Maoxiao; Li, Zhi; Cardoso, João; Niu, Donghong; Liu, Xiaojun; Dong, Zhiguo; Li, Jiale; Power, DeborahComplement proteins emerged early in evolution but outside the vertebrate clade they are poorly characterized. An evolutionary model of C3 family members revealed that in contrast to vertebrates the evolutionary trajectory of C3-like genes in cnidarian, protostomes and invertebrate deuterostomes was highly divergent due to independent lineage and species-specific duplications. The deduced C3-like and vertebrate...
RNAi-mediated knock-down of the dopamine beta-hydroxylase gene changes growth o...
Li, Zhi; Peng, Maoxiao; Power, Deborah; Niu, Donghong; Dong, Zhiguo; Li, JialeDopamine beta-hydroxylase (D beta H) plays an essential role in the synthesis of catecholamines (CA) in neuroen-docrine networks. In the razor clam, Sinonovacula constricta a novel gene for D beta H (ScD beta H-alpha) was identified that belongs to the copper type II ascorbate-dependent monooxygenase family. Expression analysis revealed ScD beta H-alpha gene transcripts were abundant in the liver and expressed ...
Dopamine beta-hydroxylase and its role in regulating the growth and larval meta...
Li, Zhi; Niu, Donghong; Peng, Maoxiao; Xiong, Ya; Ji, Jie; Dong, Zhiguo; Li, JialeDopamine beta-hydroxylase (D beta H) plays a key role in the synthesis of catecholamines (CAs) in the neuroendocrine regulatory network. The D beta H gene was identified from the razor clam Sinonovacula constricta and referred to as ScD beta H. The ScD beta H gene is a copper type II ascorbate-dependent monooxygenase with a DOMON domain and two Cu2_monooxygen domains. ScD beta H transcript expression was abunda...