Background Accurate and practical outcome measures for clinical trials in systemic lupus erythematosus (SLE) are lacking. The SLE Disease Activity Score (SLE-DAS) is a recently validated 17-item instrument, with high accuracy and sensitivity to changes in SLE disease activity. The SLE-DAS definitions of remission and low disease activity (LDA) were newly validated in the clinical setting1,2. These definitions m...
Background Accurate and practical outcome measures for clinical trials in systemic lupus erythematosus (SLE) are lacking. The SLE Disease Activity Score (SLE-DAS) is a recently validated 17-item instrument, with high accuracy and sensitivity to changes in SLE disease activity. The SLE-DAS definitions of remission and low disease activity (LDA) were newly validated against disease activity physician-applied meas...
Made available in DSpace on 2022-05-02T18:42:56Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-05-14; A measurement of the Higgs boson mass is presented based on the combined data samples of the ATLAS and CMS experiments at the CERN LHC in the H→γγ and H→ZZ→4 decay channels. The results are obtained from a simultaneous fit to the reconstructed invariant mass peaks in the two channels and for the two exp...
Made available in DSpace on 2022-05-03T17:58:33Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-05-14; A measurement of the Higgs boson mass is presented based on the combined data samples of the ATLAS and CMS experiments at the CERN LHC in the H→γγ and H→ZZ→4 decay channels. The results are obtained from a simultaneous fit to the reconstructed invariant mass peaks in the two channels and for the two exp...
Made available in DSpace on 2020-12-10T20:14:30Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-08-12; ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWFW, Austria; FWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); NSERC, Canada; CFI, Canada; CONICYT, Chile; NSFC, China;...
Made available in DSpace on 2019-10-04T19:27:06Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-05-16; ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWFW, Austria; FWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); NSERC, Canada; NRC, Canada; CFI, Canada; CERN; CONICYT, ...
Made available in DSpace on 2018-11-26T17:56:10Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-07-18; ANPCyT (Argentina); YerPhI (Armenia); ARC (Australia); BMWFW (Austria); FWF (Austria); ANAS (Azerbaijan); SSTC (Belarus); FNRS (Belgium); FWO (Belgium); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de ...
Made available in DSpace on 2018-11-26T20:09:02Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-04-09; ANPCyT (Argentina); YerPhI (Armenia); ARC (Australia); BMWFW (Austria); FWF (Austria); ANAS (Azerbaijan); SSTC (Belarus); FNRS (Belgium); FWO (Belgium); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de ...
Made available in DSpace on 2018-11-26T22:16:26Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-05-14; ANPCyT (Argentina); YerPhI (Armenia); ARC (Australia); BMWFW (Austria); FWF (Austria); ANAS (Azerbaijan); SSTC (Belarus); FNRS (Belgium); FWO (Belgium); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de ...
Systemic lupus erythematosus (SLE) is an autoimmune disease with marked gender and ethnic disparities. We report a large transancestral association study of SLE using Immunochip genotype data from 27,574 individuals of European (EA), African (AA) and Hispanic Amerindian (HA) ancestry. We identify 58 distinct non-HLA regions in EA, 9 in AA and 16 in HA (∼50% of these regions have multiple independent association...