7 documents found, page 1 of 1
Overview of artemisinin effectiveness during outset years of its implementation...
Pinto, Raquel de Medeiros; Sampaio, Vanderson de Souza; Melo, Gisely Cardoso de; Alecrim, Maria das Graças Costa; Mattos, KarineBACKGROUND The elimination of malaria depends on the blocking of transmission and of an effective treatment. In Brazil, artemisinin therapy was introduced in 1991, and here we present a performance overview during implementation outset years. METHODS It is a retrospective cohort (1991 to 2002) of patients treated in a tertiary centre of Manaus, with positive microscopic diagnosis of Plasmodium falciparum malari...
Do climate changes alter the distribution and transmission of malaria? Evidence...
Cella, Wilsandrei; Silva, Djane Clarys Baia da; Melo, Gisely Cardoso de; Tadei, Wanderli Pedro; S. Sampaio, Vanderson; Pimenta, Paulo Filemon PaolucciMalaria, a mosquito-borne infectious disease, is considered a significant global health burden. Climate changes or different weather conditions may impact infectious diseases, specifically those transmitted by insect vectors and contaminated water. Based on the current predictions for climate change associated with the increase in carbon dioxide concentrations in the atmosphere and the increase in atmospheric t...
Micronutrient deficiencies and plasmodium vivax malaria among children in the B...
Benzecry, Silvana Gomes; Alexandre, Márcia Almeida A.Araújo; Vítor-Silva, Sheila; Salinas, Jorge L.; Melo, Gisely Cardoso deBackground: There is a growing body of evidence linking micronutrient deficiencies and malaria incidence arising mostly from P. falciparum endemic areas. We assessed the impact of micronutrient deficiencies on malaria incidence and vice versa in the Brazilian state of Amazonas. Methodology/Principal Findings: We evaluated children <10 years old living in rural communities in the state of Amazonas, Brazil, from ...
Integrated vector management targeting Anopheles darlingi populations decreases...
Martins-Campos, Keillen M.; Pinheiro, Waléria Dasso; Vítor-Silva, Sheila; Siqueira, Andre M.; Melo, Gisely Cardoso de; Rodrigues, Íria C.Background: Studies on vector behaviour should be conducted in order to evaluate the effectiveness of vector control measures on malaria protection in endemic areas of Latin America, where P. vivax predominates. This work aims to investigate the fauna of anopheline mosquitoes and verify the impact of integrated vector management in two colonization projects in the Careiro Municipality, Western Brazilian Amazon....
Overview of artemisinin effectiveness during outset years of its implementation...
Pinto, Raquel de Medeiros; Sampaio, Vanderson de Souza; Melo, Gisely Cardoso de; Costa Alecrimm, Maria das Gracas; Mattoss, KarineMade available in DSpace on 2019-10-06T00:01:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-01-01. Added 1 bitstream(s) on 2019-10-09T18:34:40Z : No. of bitstreams: 1 S0074-02762019000100320.pdf: 970993 bytes, checksum: 3b020cb8d2ae9b27e9127d6bc5080a06 (MD5); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); BACKGROUND The elimination of malaria depends on the blocking of transmiss...
G6PD deficiency in Latin America : systematic review on prevalence and variants
Monteiro, Wuelton Marcelo; Val, Fernando Fonseca de Almeida; Siqueira, André Machado; Franca, Gabriel Peixoto; Sampaio, Vanderson de SouzaPlasmodium vivax radical cure requires the use of primaquine (PQ), a drug that induces haemolysis in glucose-6-phosphate dehydrogenase deficient (G6PDd) individuals, which further hampers malaria control efforts. The aim of this work was to study the G6PDd prevalence and variants in Latin America (LA) and the Caribbean region. A systematic search of the published literature was undertaken in August 2013. Biblio...
Clinical complications of G6PD deficiency in Latin American and Caribbean popul...
Monteiro, Wuelton Marcelo; Franca, Gabriel Peixoto; Melo, Gisely Cardoso de; Queiroz, Amanda de Lourdes Maciel; Brito, Marcelo; Peixoto, Henry MaiaBackground: Although G6PDd individuals are generally asymptomatic throughout their life, the clinical burden of this genetic condition includes a range of haematological conditions, including acute haemolytic anaemia (AHA), neonatal jaundice (NNJ) and chronic non-sphaerocytic anaemia (CNSA). In Latin America (LA), the huge knowledge gap regarding G6PDd is related to the scarce understanding of the burden of cli...