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Establishment, molecular and biological characterization of HCB-514: a novel hu...

Rosa, Marcela Nunes; Evangelista, Adriane Feijó; Leal, Letícia Ferro; De Oliveira, Cristina Mendes; Silva, Viviane Aline Oliveira

Cervical cancer is the fourth most common cancer in women. Although cure rates are high for early stage disease, clinical outcomes for advanced, metastatic, or recurrent disease remain poor. To change this panorama, a deeper understanding of cervical cancer biology and novel study models are needed. Immortalized human cancer cell lines such as HeLa constitute crucial scientific tools, but there are few other ce...


Squamous differentiation portends poor prognosis in low and intermediate-risk e...

Andrade, Diocesio Alves Pinto de; da Silva, Vinicius Duval; Matsushita, Graziela de Macedo; de Lima, Marcos Alves; Vieira, Marcelo de Andrade

Endometrial cancer presents well-defined risk factors: myometrial invasion, histological subtype, tumor grade, lymphovascular space invasion (LVSI). Some low and intermediate-risk endometrioid endometrial cancer patients exhibited unexpected outcomes. This study aimed to investigate other clinical-pathological factors that might influence the recurrence rates of patients diagnosed with low and intermediate-risk...


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