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The Aspergillus fumigatus Mismatch Repair MSH2 Homolog Is Important for Virulen...

Dos Reis, Thaila Fernanda; Silva, Lilian Pereira; de Castro, Patrícia Alves; do Carmo, Rafaela Andrade; Marini, Marjorie Mendes

The genetic stability of every living organism depends on accurate DNA replication and repair systems. Here, we investigated the Aspergillus fumigatusMSH2 mismatch repair (MMR) gene MshA and how it impacts virulence and the evolution of azole resistance. We examined mshA gene variation in 62 environmental and clinical A. fumigatus strains. We have observed 12 strains with variants (18.2%), and 8 strains among t...


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