3 documents found, page 1 of 1
Discovery of (E)-4-styrylphenoxy-propanamide: A dual PPARα/γ partial agonist th...
Dutra, Luiz A. [UNESP]; Lacerda, Mariella G.; Destro Inácio, Maiara [UNESP]; Martins, Johnny W.L. [UNESP]; Lopes Silva, Ana C. [UNESP]Made available in DSpace on 2022-04-29T08:46:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-03-01; Peroxisome proliferator-activated receptors are promising therapeutic targets for metabolic diseases, including obesity, diabetes, and dyslipidemia. This study describes the design, synthesis and pharmacological evaluation of stilbene-based compounds as dual PPARα/γ partial agonists with potency in the ...
Benzofuroxan Derivatives as Potent Agents against Multidrug-Resistant Mycobacte...
Fernandes, Guilherme F. S. [UNESP]; Campos, Débora L. [UNESP]; Da Silva, Isabel C. [UNESP]; Prates, João L. B. [UNESP]; Pavan, Aline R. [UNESP]Made available in DSpace on 2021-06-25T11:11:25Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-04-20; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Tuberculosis (TB) is currently the leading cause of death related to infectious diseases worldwide, as reported by the World Health Organization. Moreover, the increasing ...
Antiplatelet activity and TNF-α release inhibition of phthalimide derivatives u...
Chelucci, Rafael C. [UNESP]; de Oliveira, Isabela J. [UNESP]; Barbieri, Karina P. [UNESP]; Lopes-Pires, Maria E.; Polesi, Marisa C. [UNESP]Made available in DSpace on 2019-10-06T15:44:48Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-08-01; Sickle Cell Anemia (SCA) is one of the most prevalent hereditary hematological diseases worldwide. The disease is characterized by chronic inflammation, hypercoagulable state, and pro-thrombotic profile, which lead the vaso-occlusive process. In this work, we described the antiplatelet activity and the ...