5 documents found, page 1 of 1
A voz materna e o bebê prematuro: questões sobre a comunicação no ambiente hosp...
Dourado, AnaSubmitted by ANA DOURADO (ana_dourado@hotmail.com) on 2018-03-26T18:48:31Z No. of bitstreams: 1 Ana Dourado dissertação (FIM) revisão.pdf: 1998476 bytes, checksum: 25de93e8be4b8e200bd78371256a6a5a (MD5); Approved for entry into archive by Luciana Pizzani null (luciana@btu.unesp.br) on 2018-03-26T20:18:27Z (GMT) No. of bitstreams: 1 dourado_a_me_bot.pdf: 1973702 bytes, checksum: f1aa9989713b18249ac2b4e83ff7a8...
Family association study between DRD2 and DRD3 gene polymorphisms and schizophr...
Ambrósio, Alda M.; Kennedy, James L.; Macciardi, Fabio; Macedo, António; Valente, José; Dourado, Ana; Oliveira, Catarina R.; Pato, CarlosSchizophrenia is a highly heritable condition, as demonstrated in family, twin and adoption studies. Candidate genes from the dopaminergic system have long been hypothesized to be involved in the etiology of this disorder. In the present study, we investigated the genetic association between polymorphisms in the D2 and D3 dopamine receptor (DRD2, DRD3) genes and schizophrenia. We examined 90 trios from Portugal...
NR4A2 and schizophrenia: Lack of association in a Portuguese/Brazilian study
Ruano, Dina; Macedo, António; Dourado, Ana; Soares, Maria João; Valente, José; Coelho, Isabel; Santos, Vítor; Azevedo, Maria Helena; Goodman, AnnThe present study investigates the association of mutations in the nuclear receptor NR4A2 in schizophrenic patients. The human Nur-related receptor 1, NR4A2, is an orphan nuclear receptor that can be constitutively active as a transcription factor and for which no natural ligand has yet been identified. Alone or with retinoid X receptor, RXR, NR4A2 influences the expression of several genes important for human ...
NR4A2 and schizophrenia: lack of association in a portuguese/brazilian study
Ruano, Dina; Macedo, António; Dourado, Ana; Soares, Maria João; Valente, José; Coelho, Isabel; Santos, Vítor; Azevedo, Maria Helena; Goodman, AnnThe present study investigates the association of mutations in the nuclear receptor NR4A2 in schizophrenic patients. The human Nur-related receptor 1, NR4A2, is an orphan nuclear receptor that can be constitutively active as a transcription factor and for which no natural ligand has yet been identified. Alone or with retinoid X receptor, RXR, NR4A2 influences the expression of several genes important for human ...
Evidence for linkage disequilibrium between the alpha 7-nicotinic receptor gene...
Xu, Junzhe; Pato, Michele T.; Torre, Camille Dalla; Medeiros, Helena; Carvalho, Célia; Basile, Vincenzo S.; Bauer, Amy; Dourado, Ana; Valente, JoséRecent studies have suggested that the alpha 7-nicotinic receptor gene (CHRNA7) may play a role in the pathogenesis of schizophrenia. The alpha 7-nicotinic receptor gene (CHRNA7) is involved in P50 auditory sensory gating deficits, and the genomic locus for this gene lies in the chromosome 15q13-14 regions. The human gene is partially duplicated (exons 5-10) with four novel upstream exons. The marker D15S1360 h...