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Guidelines’ recommendations for the treatment-resistant depression: A systemati...

Gabriel, Franciele Cordeiro; Stein, Airton Tetelbom; Melo, Daniela de Oliveira; Fontes-Mota, Gessica Caroline Henrique; dos Santos, Itamires Benício

Introduction: Depression is a serious and widespread mental health disorder. A significant proportion of patients with depression fail to remit after two antidepressant treatment trials, a condition named treatment-resistant depression (TRD). Clinical practice guidelines (CPGs) are instruments aimed to improve diagnosis and treatment. This study objective is to systematically appraise the quality and elaborate ...


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