18 documents found, page 1 of 2
A numerical methodology to support the development of liquid adhesive spreading...
Bastos, Lourenço; Duarte, F. M.; Viana, J. C.; Silva, Filipe; Nogueira, Miguel; Carneiro, FilipaA numerical methodology was implemented to support the development of adhesive spreading patterns for the Optical Bonding (OB) material on display bonding process, in order to reduce the experimental trial and error effort, being this iterative process done mainly through numerical simulations. These simulations were performed using the commercial software Abaqus, more specifically the Abaqus/Explicit module, w...
Transmission laser welding of thermoplastics: influence of welding parameters a...
Bastos, Lourenço; Alves, Marco; Sousa, Bruno; Vilela, Andreia; Rietter, Luciano; Duarte, F. M.; Carneiro, Filipa; Żmijewska-Rocha, AgnieszkaLaser transmission welding of injection moulded thermoplastics is commonly used in industrial applications such as electronic packaging, textiles, biomedical devices, windows, signs, food and medical packaging, visual displays and automotive components due to very precise control of the process parameters, including the amount of energy delivered and its location, which results in high joint quality. In this ar...
Anxiety and depression in patients with prostate cancer, at cancer diagnosis an...
Duarte, Vítor; Araújo, Natália; Lopes, Catarina; Costa, Adriana; Ferreira, Augusto; Carneiro, Filipa; Oliveira, Jorge; Braga, Isaac; Morais, SamanthaProstate cancer (PCa) is the most prevalent among men, and psychological symptoms may affect many patients. This study aims to describe the prevalence of probable anxiety and depression before PCa treatments and after one year and to identify sociodemographic and clinical factors associated with these outcomes. Between February 2018 and March 2020, 292 patients recently diagnosed with PCa were recruited at the ...
Prevalence of cognitive impairment before prostate cancer treatment
Araújo, Natália; Costa, Adriana; Lopes, Catarina; Lopes-Conceição, Luisa; Ferreira, Augusto; Carneiro, Filipa; Oliveira, Jorge; Morais, SamanthaCognitive impairment is common among patients with different types of cancer, even before cancer treatment, but no data were reported among patients with prostate cancer (PCa), who may be at high risk due to advanced age. This study aims to estimate the prevalence of cognitive impairment before PCa treatment. Between February 2018 and April 2021, the NEON-PC cohort recruited 605 patients with PCa proposed for t...
Numerical study of the unsteady flow in simplified and realistic iliac bifurcat...
Carvalho, Violeta Meneses; Carneiro, Filipa; Ferreira, Ana C. M.; Gama, Vasco; Teixeira, J. Carlos; Teixeira, S. F. C. F.Cardiovascular diseases are a major cause of death and disability worldwide and they are commonly associated with the occurrence of atherosclerotic plaque deposition in the vessel walls, a process denoted as atherosclerosis. This is a chronic and progressive inflammatory disease of large-/medium-sized blood vessels that affects blood flow profiles, with the abdominal aorta and its branches being one of the loca...
Usability Assessment of an Innovative Device in Infusion Therapy: A Mix-Method ...
Parreira, Pedro; Sousa, Liliana B.; Marques, Inês A.; Santos-Costa, Paulo; Cortez, Sara; Carneiro, Filipa; Cruz, Arménio; Salgueiro-Oliveira, AnabelaBackground: Flushing a venous access device is an important procedure to maintain their patency and prevent malfunctioning and complications. An innovative double-chamber syringe was developed, allowing for the assessment of catheter patency, drug delivery and final flush. This study aims to assess the usability of this new device, considering three development stages (concept, semi-functional prototype, functi...
Study Protocol for Two-Steps Parallel Randomized Controlled Trial: Pre-Clinical...
Parreira, Pedro; Sousa, Liliana B.; Marques, Inês A.; Santos-Costa, Paulo; Cortez, Sara; Carneiro, Filipa; Cruz, Arménio; Salgueiro-Oliveira, AnabelaA new double-chamber syringe (DUO Syringe) was developed for intravenous drug administration and catheter flushing. This study presents a protocol for pre-clinical usability tests to validate the golden prototype of this new device, performed in a high-fidelity simulation lab by nurses. A two-steps parallel randomized controlled trial with two arms was designed (with standard syringes currently used in clinical...
Development of an innovative double-chamber syringe for intravenous therapeutic...
Parreira, Pedro; Sousa, Liliana B.; Marques, Inês A.; Costa, Paulo; Cortez, Sara; Carneiro, Filipa; Cruz, Arménio; Salgueiro-Oliveira, AnabelaIn nursing practice, flushing the catheters pre and post-drug administration is considered an important clinical procedure to prevent complications, and requires the use of several syringes to comply with international standards of care. We envisioned an innovative double-chamber syringe that enables the filling and administration of both solutions. Following current international recommendations, the developme...
Combining 1,3-ditriazolyl-benzene and quinoline to discover a new G-quadruplex ...
Mendes, Maria Eduarda; Cadoni, Enrico; Carneiro, Filipa; Afonso, Marta; Brito, Hugo; Lavrado, João; Santos, Daniel J. V. A. dos; Vítor, Jorge M. B.Quadruplex nucleic acids are promising targets for cancer therapy. In this study we used a fragment-based approach to create new flexible G-quadruplex (G4) DNA-interactive small molecules with good calculated oral drug-like properties, based on quinoline and triazole heterocycles. G4 melting temperature and polymerase chain reaction (PCR)-stop assays showed that two of these compounds are selective G4 ligands, ...
Relação entre a adesão à dieta mediterrânica e o desempenho escolar em adolesce...
Cardoso, Cristina; Pereira, Diana; Carneiro, Filipa; Almeida, Mariana; Fernandes, António; Ferro-Lebres, VeraUma dieta saudável tem sido associada ao desempenho académico. Por essa razão, este trabalho teve como objetivo estudar a relação entre antropometria, Dieta Mediterrânica e desempenho académico. A adesão à Dieta Mediterrânica foi avaliada através do índice KidMed. O desempenho académico foi avaliado pelo valor médio das notas finais. Foram, ainda, recolhidos dados antropométricos. O estudo incluiu 449 adolescen...