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Topical caffeine delivery using biocellulose membranes: a potential innovative ...

Silva, Nuno H. C. S.; Drumond, Ines; Almeida, Isabel F.; Costa, Paulo; Rosado, Catarina F.; Neto, Carlos Pascoal; Freire, Carmen S. R.

In this study, biocellulose (BC) membranes have been investigated as caffeine topical delivery systems, for the potential treatment of cellulite. BC-caffeine membranes were prepared by a simple approach and the permeation of caffeine through human epidermis, from BC or from conventional formulation systems (solution and gel), was compared in vitro to assess their therapeutic applicability. Diffusion studies wit...


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