Bravo de Esmolfe (BE) is a traditional Portuguese apple highly appreciated by consumers due to its peculiar flavor and aroma. This apple contains higher concentration of phenolic compounds than other cultivars and is thus considered a rich source of antioxidants. Its sensorial and functional properties have attracted farmers' associations to increase BE production. However, a large quantity of apples is wasted ...
Curcumin nanoemulsions stabilized by whey protein isolate were successfully developed using high-pressure homogenization. The effect of a chitosan layer deposition using the layer-by-layer technique on nanoemulsions' stability was evaluated during storage conditions, as well as during gastrointestinal tract passage. Lipids hydrolysis and curcumin bioaccessibility was assessed using a dynamic gastrointestinal mo...
Nanoemulsions can be used to improve the bioaccessibility of lipophilic bioactive compounds, such as curcumin, being their behaviour highly influenced by their interfacial properties. The effect of chitosan and alginate layers deposition on curcumin nanoemulsions behaviour during in vitro digestion was evaluated using a dynamic gastrointestinal system. Results showed that polyelectrolyte layers deposition impro...
[Excerpt] Introduction: Curcumin, a natural polyphenolic phytochemical, is known for its wide range of biological activities, however it has an extremely low water solubility as well as a low bioavailability, which limit its application as a bioactive ingredient in food. The use of delivery systems at nanoscale such as nanoemulsions (NE) and solid lipid nanoparticles (SLN) has been reported as a promising mean ...
Nanotechnology is pointed to as one of the hot topics in food science and technology where the use of nanostructured systems for compounds delivery using biobased materials appears as one of the most interesting matters in the field. Due to their advantages when compared with micro- and macroscale systems, nanostructured biobased systems have attracted a great interest from academia and industry where they can ...
Novel ionic liquids (ILs) containing cholinium as a benign cation combined with anions based on five active pharmaceutical ingredients (APIs), namely, nalidixic acid, niflumic acid, 4-amino-salicylic acid, pyrazinoic acid and picolinic acid, were prepared via a simple and sustainable two-step anion exchange reaction. The solubility of the prepared pharmaceutically active ILs (API-ILs) in both water and simulate...
Faster and more selective extraction methods are urged to recover food-grade pigments and antioxidants from microalgae - which do not resort to food-incompatible and environment-unfriendly solvents. Hence, this study ascertained the influence of pressure, temperature, CO2 flow rate and a polar co-solvent upon the yields of carotenoids and chlorophylls in supercritical fluid extraction of Scenedesmus obliquus bi...
[Excerto] Tem sido crescente a evidência de que nanopartículas podem induzir toxicidade celular relevante com forte impacto na saúde humana. Esta toxicidade pode ser expressa através da indução de diversas respostas celulares tais como a morte celular, inflamação e stress oxidativo, tornando-se assim de extrema importância a utilização de modelos celulares in vitro para avaliar a resposta biológica desencadeada...
Ionic liquids have become a green media for engineering applications due to exceptional physicochemical properties, such as their practically nonvolatile nature, null flammability, low melting point, high ionic conductivity, and thermal and electrochemical stability. This work aimed to select the best fluorinated ionic liquids for the following applications: recovery/recycling of perfluorocarbon contaminants su...